DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstD2 and Clic4

DIOPT Version :9

Sequence 1:	NP_524912.1	Gene:	GstD2 / 48335	FlyBaseID:	FBgn0010038	Length:	215	Species:	Drosophila melanogaster
Sequence 2:	NP_114006.1	Gene:	Clic4 / 83718	RGDID:	61857	Length:	253	Species:	Rattus norvegicus

Alignment Length:	170	Identity:	40/170 - (23%)
Similarity:	67/170 - (39%)	Gaps:	46/170 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 KLLNTMEGEQLKPEFVKLNPQHTIPTLVDNGFSIWESRAIAVYLVEKYGKDDYLLPNDPKKRAVI 93
            |:...:|.....|:::||:|:|.            ||....:.:..|:..  |:..:.|:....:
  Rat    90 KIEEFLEEVLCPPKYLKLSPKHP------------ESNTAGMDIFAKFSA--YIKNSRPEANEAL 140

  Fly    94 NQRLYFDMGTLYESFAKYYYPLFRTGKPG-----SDEDLKRIETAFGFLDTFLEGQEYVAGDQLT 153
            .:.|   :.||.:.......||     ||     |.||:|  .:...|||          ||::|
  Rat   141 ERGL---LKTLQKLDEYLNSPL-----PGEIDENSMEDIK--SSTRRFLD----------GDEMT 185

  Fly   154 VADIAILSTVSTFEVSEFDFSKYSNVSRWYDNAKKVTPGW 193
            :||..:|..:...:|..   .||.|    :|..|.:|..|
  Rat   186 LADCNLLPKLHIVKVVA---KKYRN----FDIPKGMTGIW 218

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstD2	NP_524912.1	GST_N_Delta_Epsilon	1..74	CDD:239343	9/44 (20%)
GstD2	NP_524912.1	GST_C_Delta_Epsilon	88..204	CDD:198287	28/111 (25%)
Clic4	NP_114006.1	Required for insertion into the membrane. /evidence=ECO:0000250	2..101		2/10 (20%)
		GST_N_CLIC	14..104	CDD:239359	3/13 (23%)
		O-ClC	17..252	CDD:129941	40/170 (24%)
		GST_C_family	111..251	CDD:295467	34/149 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166347841
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930