DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstD2 and GstE8

DIOPT Version :9

Sequence 1:	NP_524912.1	Gene:	GstD2 / 48335	FlyBaseID:	FBgn0010038	Length:	215	Species:	Drosophila melanogaster
Sequence 2:	NP_001286571.1	Gene:	GstE8 / 37113	FlyBaseID:	FBgn0063492	Length:	222	Species:	Drosophila melanogaster

Alignment Length:	189	Identity:	72/189 - (38%)
Similarity:	114/189 - (60%)	Gaps:	10/189 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 RTVIMVAKALGLELNKKLLNTMEGEQLKPEFVKLNPQHTIPTLVDNGFSIWESRAIAVYLVEKYG 77
            |...:...|||:......:||:..|.|.|||::.|||||:|||.|:|..||:|.||:.|||.|||
  Fly    16 RAAKLTLAALGIPYEYVKINTLAKETLSPEFLRKNPQHTVPTLEDDGHFIWDSHAISAYLVSKYG 80

  Fly    78 KDDYLLPNDPKKRAVINQRLYFDMGTLY----ESFAKYYYPLFRTGKPG-SDEDLKRIETAFGFL 137
            :.|.|.|.|..:|||::|||:|:.|.::    ....|   |||.||:.. ..|....:...:.|:
  Fly    81 QSDTLYPKDLLQRAVVDQRLHFESGVVFVNGLRGITK---PLFATGQTTIPKERYDAVIEIYDFV 142

  Fly   138 DTFLEGQEYVAGDQLTVADIAILSTVSTFEV-SEFDFSKYSNVSRWYDNAKKVTPGWDE 195
            :|||.|.:::||||||:||.:::::::...| ...|..||:|::.|....::: |.::|
  Fly   143 ETFLTGHDFIAGDQLTIADFSLITSITALAVFVVIDTVKYANITAWIKRIEEL-PYYEE 200

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstD2	NP_524912.1	GST_N_Delta_Epsilon	1..74	CDD:239343	28/60 (47%)
GstD2	NP_524912.1	GST_C_Delta_Epsilon	88..204	CDD:198287	36/114 (32%)
GstE8	NP_001286571.1	GstA	4..196	CDD:223698	70/183 (38%)
		GST_N_Delta_Epsilon	4..77	CDD:239343	28/60 (47%)
		GST_C_Delta_Epsilon	91..209	CDD:198287	36/114 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45460250
Domainoid	1	1.000	54	1.000	Domainoid score	I4138
eggNOG	1	0.900	-	-		E1_COG0625
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	77	1.000	Inparanoid score	I2398
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1231780at2759
OrthoFinder	1	1.000	-	-		FOG0000035
OrthoInspector	1	1.000	-	-		mtm975
orthoMCL	1	0.900	-	-		OOG6_100130
Panther	1	1.100	-	-	P	PTHR43969
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X30
	11	10.800