DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstD2 and GstE7

DIOPT Version :9

Sequence 1:	NP_524912.1	Gene:	GstD2 / 48335	FlyBaseID:	FBgn0010038	Length:	215	Species:	Drosophila melanogaster
Sequence 2:	NP_611329.1	Gene:	GstE7 / 37112	FlyBaseID:	FBgn0063493	Length:	223	Species:	Drosophila melanogaster

Alignment Length:	190	Identity:	81/190 - (42%)
Similarity:	112/190 - (58%)	Gaps:	12/190 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 RTVIMVAKALGLELNKKLLNTMEGEQLKPEFVKLNPQHTIPTLVDNGFSIWESRAIAVYLVEKYG 77
            |.|.:...||.:......:||...|....||:|.|||||:|||.|:|..||:|.||..|||.|||
  Fly    16 RAVKLTLAALEVPYEFVEVNTRAKENFSEEFLKKNPQHTVPTLEDDGHYIWDSHAIIAYLVSKYG 80

  Fly    78 KDDYLLPNDPKKRAVINQRLYFDMGTLY----ESFAKYYYPLFRTGKPG--SDEDLKRIETAFGF 136
            |.|.|.|.|..:|||::|||:|:.|.::    .|..|   ||| .||..  ..|....|...:.|
  Fly    81 KTDSLYPKDLLQRAVVDQRLHFESGVIFANALRSITK---PLF-AGKQTMIPKERYDAIIEVYDF 141

  Fly   137 LDTFLEGQEYVAGDQLTVADIAILSTVSTFEV-SEFDFSKYSNVSRWYDNAKKVTPGWDE 195
            |:.||.|.:||||:|||:||.:|:||||:.|| .:.|.:||..::.|:...:|: |.::|
  Fly   142 LEKFLAGNDYVAGNQLTIADFSIISTVSSLEVFVKVDTTKYPRIAAWFKRLQKL-PYYEE 200

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstD2	NP_524912.1	GST_N_Delta_Epsilon	1..74	CDD:239343	27/60 (45%)
GstD2	NP_524912.1	GST_C_Delta_Epsilon	88..204	CDD:198287	45/115 (39%)
GstE7	NP_611329.1	GstA	4..196	CDD:223698	79/184 (43%)
		GST_N_Delta_Epsilon	4..77	CDD:239343	27/60 (45%)
		GST_C_Delta_Epsilon	91..209	CDD:198287	45/115 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45460256
Domainoid	1	1.000	54	1.000	Domainoid score	I4138
eggNOG	1	0.900	-	-		E1_COG0625
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	77	1.000	Inparanoid score	I2398
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1231780at2759
OrthoFinder	1	1.000	-	-		FOG0000035
OrthoInspector	1	1.000	-	-		mtm975
orthoMCL	1	0.900	-	-		OOG6_100130
Panther	1	1.100	-	-	P	PTHR43969
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X30
	11	10.800