Protein Alignment GstD2 and GSTA4

DIOPT Version :10

• Sequence 1: NP_524912.1
• Gene: GstD2 / 48335
• FlyBaseID: FBgn0010038
• Length: 215
• Species: Drosophila melanogaster
• Sequence 2: NP_001503.1
• Gene: GSTA4 / 2941
• HGNCID: 4629
• Length: 222
• Species: Homo sapiens
• Alignment Length: 238
• Identity: 51/238 - (21%)
• Similarity: 89/238 - (37%)
• Gaps: 81/238 - (34%)

  Fly     4 YYMPGGGGCRTVIMVAKALGLELNKKLLNTMEGEQLKPEFVKLNPQH-----TIPTLVDNGFSIW 63
            :|..|.|...:|..|..|.|:|.:::.|.|      |.:..||...:     .:|.:..:|..:.
Human     8 HYPNGRGRMESVRWVLAAAGVEFDEEFLET------KEQLYKLQDGNHLLFQQVPMVEIDGMKLV 66

  Fly    64 ESRAIAVYLVEK---YGKD------------------------DYLLPNDPKKRAVINQRLYFDM 101
            ::|:|..|:.:|   :||:                        .:|.|:|.:|..|
Human    67 QTRSILHYIADKHNLFGKNLKERTLIDMYVEGTLDLLELLIMHPFLKPDDQQKEVV--------- 122

  Fly   102 GTLYESFAKYYYPLFRTGKPGSDEDLKRIETAFGFLDTFLEGQEYVAGDQLTVADIAILSTVSTF 166
             .:.:.....|:|:|.....|                   .||.::.|:||::||:.:|.|:...
Human   123 -NMAQKAIIRYFPVFEKILRG-------------------HGQSFLVGNQLSLADVILLQTILAL 167

  Fly   167 E------VSEFDF-----SKYSN---VSRWYDNAKKVTPGWDE 195
            |      :|.|.|     .|.||   :.|:.:...|..|..||
Human   168 EEKIPNILSAFPFLQEYTVKLSNIPTIKRFLEPGSKKKPPPDE 210

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GstD2	NP_524912.1	GST_N_Delta_Epsilon	1..74	CDD:239343	18/74 (24%)
		GST_C_Delta_Epsilon	88..204	CDD:198287	27/122 (22%)
GSTA4	NP_001503.1	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold	4..82	CDD:469754	19/79 (24%)
		GST_C_Alpha	86..220	CDD:198317	30/154 (19%)