DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstD2 and CLIC4

DIOPT Version :9

Sequence 1:	NP_524912.1	Gene:	GstD2 / 48335	FlyBaseID:	FBgn0010038	Length:	215	Species:	Drosophila melanogaster
Sequence 2:	NP_039234.1	Gene:	CLIC4 / 25932	HGNCID:	13518	Length:	253	Species:	Homo sapiens

Alignment Length:	165	Identity:	34/165 - (20%)
Similarity:	66/165 - (40%)	Gaps:	36/165 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 KLLNTMEGEQLKPEFVKLNPQHTIPTLVDNGFSIWESRAIAVYLVEKYGKDDYLLPNDPKKRAVI 93
            |:...:|.....|:::||:|:|.            ||....:.:..|:..  |:..:.|:....:
Human    90 KIEEFLEEVLCPPKYLKLSPKHP------------ESNTAGMDIFAKFSA--YIKNSRPEANEAL 140

  Fly    94 NQRLYFDMGTLYESFAKYYYPLFRTGKPGSDEDLKRIETAFGFLDTFLEGQEYVAGDQLTVADIA 158
            .:.|   :.||.:.......||.......|.||:|            ...::::.|:::|:||..
Human   141 ERGL---LKTLQKLDEYLNSPLPDEIDENSMEDIK------------FSTRKFLDGNEMTLADCN 190

  Fly   159 ILSTVSTFEVSEFDFSKYSNVSRWYDNAKKVTPGW 193
            :|..:...:|..   .||.|    :|..|::|..|
Human   191 LLPKLHIVKVVA---KKYRN----FDIPKEMTGIW 218

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstD2	NP_524912.1	GST_N_Delta_Epsilon	1..74	CDD:239343	9/44 (20%)
GstD2	NP_524912.1	GST_C_Delta_Epsilon	88..204	CDD:198287	22/106 (21%)
CLIC4	NP_039234.1	Required for insertion into the membrane. /evidence=ECO:0000305	2..101		2/10 (20%)
CLIC4	NP_039234.1	O-ClC	17..252	CDD:129941	34/165 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165154225
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930