DRSC/TRiP Functional Genomics Resources

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Protein Alignment GstD2 and CLIC2

DIOPT Version :9

Sequence 1:NP_524912.1 Gene:GstD2 / 48335 FlyBaseID:FBgn0010038 Length:215 Species:Drosophila melanogaster
Sequence 2:NP_001280.3 Gene:CLIC2 / 1193 HGNCID:2063 Length:247 Species:Homo sapiens


Alignment Length:221 Identity:52/221 - (23%)
Similarity:91/221 - (41%) Gaps:50/221 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MDFYYMPGGGG--------CRTVIMVAKALGLELNKKLLN-TMEGEQLKPEFVKLNPQHTIPTLV 56
            ::.:...|..|        |:.:.|:....|::.|...:: |.:.|:||......||    |.||
Human    14 IELFVKAGSDGESIGNCPFCQRLFMILWLKGVKFNVTTVDMTRKPEELKDLAPGTNP----PFLV 74

  Fly    57 DNGFSIWESRAIAVYLVEKYGKDDYLLPN-DPKKRAVINQRLYFDMG-TLYESFAKYYYPLFRTG 119
            .|.....:...|..:|.:......|  |: .||.:.      .||:| .|:..|:.|   :..|.
Human    75 YNKELKTDFIKIEEFLEQTLAPPRY--PHLSPKYKE------SFDVGCNLFAKFSAY---IKNTQ 128

  Fly   120 KPGSDEDLKRIETAFGFLDTFL-----------EGQE-------YVAGDQLTVADIAILSTVSTF 166
            |..:....|.:...|..||.:|           ..:|       ::.|||||:||.::|..::..
Human   129 KEANKNFEKSLLKEFKRLDDYLNTPLLDEIDPDSAEEPPVSRRLFLDGDQLTLADCSLLPKLNII 193

  Fly   167 EVS-----EFDF-SKYSNVSRWYDNA 186
            :|:     :||. :::|.|.|:..||
Human   194 KVAAKKYRDFDIPAEFSGVWRYLHNA 219

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GstD2NP_524912.1 GST_N_Delta_Epsilon 1..74 CDD:239343 18/81 (22%)
GST_C_Delta_Epsilon 88..204 CDD:198287 31/124 (25%)
CLIC2NP_001280.3 Required for insertion into the membrane. /evidence=ECO:0000250 1..96 18/85 (21%)
N-terminal 1..94 18/83 (22%)
O-ClC 12..245 CDD:129941 52/221 (24%)
Joint loop 95..106 3/12 (25%)
C-terminal 107..247 30/122 (25%)
Foot loop 151..171 1/19 (5%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165154393
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.930

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