Protein Alignment ttk and fru

DIOPT Version :10

• Sequence 1: NP_733443.1
• Gene: ttk / 48317
• FlyBaseID: FBgn0003870
• Length: 813
• Species: Drosophila melanogaster
• Sequence 2: NP_001163648.1
• Gene: fru / 42226
• FlyBaseID: FBgn0004652
• Length: 960
• Species: Drosophila melanogaster
• Alignment Length: 894
• Identity: 217/894 - (24%)
• Similarity: 331/894 - (37%)
• Gaps: 286/894 - (31%)

  Fly     6 QRFCLRWNNHQSNLLSVFDQLLHAETFTDVTLAVEGQHLKAHKMVLSACSPYFNTLFVSHPEKHP 70
            |:||||||||.:||..|...||..|...|||||.||:.:|||:.:||||||||.|:|:.:...||
  Fly   109 QQFCLRWNNHPTNLTGVLTSLLQREALCDVTLACEGETVKAHQTILSACSPYFETIFLQNQHPHP 173

  Fly    71 IVILKDVPYSDMKSLLDFMYRGEVSVDQERLTAFLRVAESLRIKGLTEVND-------DKPSPAA 128
            |:.||||.||:|:|||||||:|||:|.|..|..||:.||||:::|||:.|:       ||...:|
  Fly   174 IIYLKDVRYSEMRSLLDFMYKGEVNVGQSSLPMFLKTAESLQVRGLTDNNNLNYRSDCDKLRDSA 238

  Fly   129 AAA-----------GAGATGSESTATTPQLQRIQPYL-------VPQRN------RSQAGGLLAS 169
            |::           |.|..|..:.|.......::...       :.||:      ||.|....|:
  Fly   239 ASSPTGRGPSNYTGGLGGAGGVADAMRESRDSLRSRCERDLRDELTQRSSSSMSERSSAAAAAAA 303

  Fly   170 AANA-----GN-----------TPTLPVQ-PSL-------LSSALMPKRKRGRPRKLS------- 203
            ||.|     ||           |||...: ||:       .::|:.........|..|
  Fly   304 AAAAVAAAGGNVNAAAVALGLTTPTGGERSPSVGSASAAAAAAAVAAAVAAAANRSASADGCSDR 368

  Fly   204 GSSNGTGN-----------DYDDFDRENMMNDSSDLGNGKMCNESYSGNDDGSDDNQPNAGHTDD 257
            ||..||..           ||.:.|..| .|.||..||    |.:.:.|::.|..|..|:....:
  Fly   369 GSERGTLERTDSRDDLLQLDYSNKDNNN-SNSSSTGGN----NNNNNNNNNNSSSNNNNSSSNRE 428

  Fly   258 LNES--------------RD-----------SLPSKRSKNSK---DHRVVSHHED---------- 284
            .|.|              ||           |...:|.|||.   |:.:.|.|:|
  Fly   429 RNNSGERERERERERERDRDRELSTTPVEQLSSSKRRRKNSSSNCDNSLSSSHQDRHYPQDSQAN 493

  Fly   285 -NSTSVTPTKATPELSQRLFGSSSTTISATAP-----GGSSTGPSETISLL--------EISDER 335
             .|:.|..|..:...|:...|...:.:|.|..     ||.:.|.:..:|.|        |:.|.:
  Fly   494 FKSSPVPKTGGSTSESEDAGGRHDSPLSMTTSVHLGGGGGNVGAASALSGLSQSLSIKQELMDAQ 558

  Fly   336 ES----------APVHLPTILGLKIRAINTTT----PAQQGSPQTPTKSKPKIRQATGSNNSNSL 386
            :.          .|.:||: ..||:.|.:.:|    .|.|.:......:..|..|...::|.:..
  Fly   559 QQQQHREHHVALPPDYLPS-AALKLHAEDMSTLLTQHALQAADARDEHNDAKQLQLDQTDNIDGR 622

  Fly   387 LK-------------------------------------QQLRGGAKDPE---------VPPATR 405
            :|                                     :...|...|||         .||..|
  Fly   623 VKCFNIKHDRHPDRELDRNHREHDDDPGVIEEVVVDHVREMEAGNEHDPEEMKEAAYHATPPKYR 687

  Fly   406 ITGAVTP-----------------NAALNAEEQSKEMPKKNQDEVNACIGLHSLANAAEQQAAQV 453
            ......|                 :...|.|.:.||            :.:.::..:.:|.....
  Fly   688 RAVVYAPPHPDEEAASGSGSDIYVDGGYNCEYKCKE------------LNMRAIRCSRQQHMMSH 740

  Fly   454 ASTGNLHHQLLL-----------------HMAANNSM--LNTTDYY---QQQQQESPSSAGQFMD 496
            .|..:.||:.|:                 ::|:|.::  |:.:.|:   ..|..:.|.||
  Fly   741 YSPHHPHHRSLIDCPAEAAYSPPVANNQAYLASNGAVQQLDLSTYHGHANHQLHQHPPSA----- 800

  Fly   497 DDLELLSLNDQQDKSDEPDHEMVTLADENAG-----LPGYQGNEAEATPAQEDSPAAETATAPPP 556
                    .........|.:...:.|...||     :.|.....|.:.||.    .|.:|.:|.|
  Fly   801 --------THPSHSQSSPHYPSASGAGAGAGSVSVSIAGSASGSATSAPAS----VATSAVSPQP 853

  Fly   557 APRS-GKKGAKRPIQRRRVRRKAQSTLDDQAEHLTEMSVRGLDLFRYASVVEGVYRCTECAKENM 620
            :..| |...:...:      ..|.:...::.:|..:.|...:.|   :..:..:|||..|
  Fly   854 SSSSTGSTSSAAAV------AAAAAAAANRRDHNIDYSTLFVQL---SGTLPTLYRCVSC----- 904

  Fly   621 QKTFKNKYSFQRHAFLYHEGKHRKVFPCPVCSKEFSRPDKMKNHLKMTH 669
            .|...|::   .||.::....|.    ||||.::|:|.|.||.|.|:.|
  Fly   905 NKIVSNRW---HHANIHRPQSHE----CPVCGQKFTRRDNMKAHCKIKH 946

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ttk	NP_733443.1	BTB_POZ_BAB-like	32..115	CDD:349624	49/82 (60%)
		PTZ00112	<184..>309	CDD:240274	40/188 (21%)
		C2H2 Zn finger	612..638	CDD:275370	6/25 (24%)
		zf-C2H2_4	646..669	CDD:464025	11/22 (50%)
		C2H2 Zn finger	648..669	CDD:275370	11/20 (55%)
fru	NP_001163648.1	BTB_POZ_BAB-like	135..218	CDD:349624	49/82 (60%)
		C2H2 Zn finger	901..918	CDD:275368	6/24 (25%)
		C2H2 Zn finger	925..944	CDD:275368	10/18 (56%)