DRSC/TRiP Functional Genomics Resources

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Protein Alignment ttk and fru

DIOPT Version :10

Sequence 1:NP_733443.1 Gene:ttk / 48317 FlyBaseID:FBgn0003870 Length:813 Species:Drosophila melanogaster
Sequence 2:XP_061511040.1 Gene:fru / 1272191 VectorBaseID:AGAMI1_010944 Length:1004 Species:Anopheles gambiae


Alignment Length:580 Identity:151/580 - (26%)
Similarity:239/580 - (41%) Gaps:160/580 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly     6 QRFCLRWNNHQSNLLSVFDQLLHAETFTDVTLAVEGQHLKAHKMVLSACSPYFNTLFVSHPEKHP 70
            |::|||||||||||.:|...||..|...|||||.|...:|||:.:||||||||..:||.:...||
Mosquito    63 QQYCLRWNNHQSNLTTVLTTLLQDEKLCDVTLACEKGMVKAHQAILSACSPYFEQIFVENKHPHP 127

  Fly    71 IVILKDVPYSDMKSLLDFMYRGEVSVDQERLTAFLRVAESLRIKGLTEVNDDKPSPAAAAAGAGA 135
            |:.|:||..::|::||||||:|||:|.|..|..||:.||||:::||||.:.|:            
Mosquito   128 IIYLRDVEVNEMRALLDFMYQGEVNVGQHNLQNFLKTAESLKVRGLTESSADR------------ 180

  Fly   136 TGSESTATTPQLQRIQPYLVPQRNRSQAGGLLASAANAGNTPTLPVQPSLLSSALMPKRKRGRPR 200
             .|..|.:..:.:||:.      :|.:...|..:::|..|                         
Mosquito   181 -YSADTDSKLRSERIRD------SRDERDSLPNASSNNSN------------------------- 213

  Fly   201 KLSGSSNGTGNDYDDFDRENMMNDSSDLGNGKMCNESYSGND--DGSDDNQPNAGHTDDLNESRD 263
               .::|.:.|:.::.:..:..|:::.|.:|.:.::..:.::  :.....|....|      .:.
Mosquito   214 ---NNNNSSSNNNNNNNTISSNNNNNSLHHGPLRDKELTEHEQLERLQQQQQQTHH------QQQ 269

  Fly   264 SLPSKRSKNSKDHRVVSHHEDNSTSVTPTKAT-PELSQRLFGSSSTTISATAPGGSSTGP----- 322
            ..||...:.|:.|....|.:       ||..| ........|...........||.|.||     
Mosquito   270 QHPSSHQQQSQQHPSSQHQQ-------PTHQTHHHHHHHQHGGGGGGGGGGGGGGGSAGPVQQPS 327

  Fly   323 -SETISLLE--ISDERE---SAPVHLPTILGLKIRAINTTTPAQQGSPQTPTKSKPKIRQATGSN 381
             |.:|.|::  :.|||:   :....:.|:...|.|.::||  ....||.||:....:........
Mosquito   328 RSASIDLMQSALVDERDYLAAEDREISTVENKKKRKLSTT--CDNSSPSTPSLMNERQGGYESQA 390

  Fly   382 NSNSLLKQQ-----------------LRG----GAKD--PEVPPATRITGAVTPNAALNAEEQSK 423
            :|:|..||.                 |.|    |.|.  ||:|....::..:.         |..
Mosquito   391 SSHSSFKQSPKPEDEFKVSSPAPVHPLAGHPLSGIKQELPELPVRHSLSSELM---------QPL 446

  Fly   424 EMPKKNQDEVNACIGL--HSLANAAEQQAAQVASTGNLHHQLLLHMAAN--NSMLNTTDYYQQQQ 484
            :|| ...||::|.|||  |:..|....::         .|.:.::|.|:  |::|          
Mosquito   447 KMP-LYADEMSASIGLEPHAHLNHLRHKS---------KHPIPINMNADDMNNIL---------- 491

  Fly   485 QESPSSAGQFMDDDLELLSLNDQQDKS---DEPDH-------EMVTLA------DENAGL 528
              :|.:.|          |||:..|..   ..|||       .|:.||      ...|||
Mosquito   492 --APGNMG----------SLNESGDSDAHLSHPDHPDNIDGDRMLRLAMASRHHHHRAGL 539

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ttkNP_733443.1 BTB_POZ_BAB-like 32..115 CDD:349624 44/82 (54%)
PTZ00112 <184..>309 CDD:240274 16/127 (13%)
C2H2 Zn finger 612..638 CDD:275370
zf-C2H2_4 646..669 CDD:464025
C2H2 Zn finger 648..669 CDD:275370
fruXP_061511040.1 None
Blue background indicates that the domain is not in the aligned region.

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