Protein Alignment ttk and Btbd18

DIOPT Version :10

• Sequence 1: NP_733443.1
• Gene: ttk / 48317
• FlyBaseID: FBgn0003870
• Length: 813
• Species: Drosophila melanogaster
• Sequence 2: NP_001417674.1
• Gene: Btbd18 / 100363270
• RGDID: 2323370
• Length: 724
• Species: Rattus norvegicus
• Alignment Length: 549
• Identity: 124/549 - (22%)
• Similarity: 184/549 - (33%)
• Gaps: 150/549 - (27%)

  Fly    23 FDQLLHAE---TFTDVTLAVEGQHLKAHKMVLSACSPYF-NTLFVSHPEKHPIVILK--DVPYSD 81
            |.||.|.:   .|.|..|..||:.:.||..:||||||:| ..|....|.:...|:|:  .:....
  Rat    21 FLQLHHQQQSGVFCDALLQAEGEAVPAHCCILSACSPFFTERLERERPVQGRKVVLELGGLKIQT 85

  Fly    82 MKSLLDFMYRGEVSVDQERLTAFLRVAESLRIKGLTEVNDDKPSPAAAAAGAGATGSESTATTPQ 146
            ::.|:||:|..|:.|.||.....|..|..||:                          |...|.|
  Rat    86 LRKLVDFLYTSEMEVSQEEAQDVLSAARQLRV--------------------------SELETLQ 124

  Fly   147 LQRIQPYLVPQRNRSQAGGLLASAANAGNTPTLPVQPSLLSSALMPKR---KRGRPRKLSGSSNG 208
            |:               ||.|..|..........:||.  |:|.:..|   .|.|||
  Rat   125 LE---------------GGKLVKAPQGRRLNRECLQPP--SAAPISARVVVPRSRPR-------- 164

  Fly   209 TGNDYDDFDRENMMNDSSDLGNGKMCNESYSGNDDGS--DDNQPNAGHTDD-----------LNE 260
                    ....:....|.||..|:   ...|.::|:  ..|.|||.:..|           |.:
  Rat   165 --------TPLPVTQTPSPLGAVKL---KSLGEEEGAHKKSNLPNADNLSDTLLLKKKARVCLTQ 218

  Fly   261 SRDSLPSKRSKNSKDHRVVSHHEDNSTSVTPTKATPELSQRLFGSS-STTISATAPGGSSTGPSE 324
            .|.|.||.:.:..|:::      .|..|.......|.:.::|.... ..:.|..:|...::.||.
  Rat   219 ERSSSPSSQREGPKENK------SNPGSTALPSLYPSVDEQLLPRKIRLSRSKPSPHVYTSKPSS 277

  Fly   325 TISLLEISDERESAPVHLPTILGLKIRAINTTTPAQQGSPQTPTKSKP---KIRQATGSNNSNSL 386
            .:          |.|..:||..|.::....|.:.|.||    ..|.||   ...|:|
  Rat   278 ML----------SGPSSMPTAPGRRLWRQRTVSEATQG----VDKQKPGEVSTLQST-------- 320

  Fly   387 LKQQLRGGAKDPEVPPATRITGAVTPNAALNAEEQSKEMPKKNQDEVNAC--IGLHSLANAAEQQ 449
                       |:.|...:..|...|:....|       |..|..|....  :.|..:.|....:
  Rat   321 -----------PDPPDVGKTGGKKQPSPESRA-------PASNSVEEGQVGRVKLRKIVNGTCWE 367

  Fly   450 AAQVASTGNLHH--QLLLHMAAN---NSMLNTTDYYQQQQQESPSSAGQFMDDDLELLSLND-QQ 508
            ..|.....|...  |:|....|:   .::|::.:     :||.|:.. |...|..|...|.| ..
  Rat   368 VVQEPPIRNTQDSPQILESSDADEPPGTLLSSVN-----EQEIPARI-QLCHDSPENSRLQDILL 426

  Fly   509 DKSDEPDHEMVTLADENAGLPGYQGNEAE 537
            ..|..|||.:|  ..|....|...|.|.|
  Rat   427 SASHSPDHPVV--KSEFGSSPMLTGKEPE 453

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ttk	NP_733443.1	BTB_POZ_BAB-like	32..115	CDD:349624	30/85 (35%)
		PTZ00112	<184..>309	CDD:240274	28/141 (20%)
		C2H2 Zn finger	612..638	CDD:275370
		zf-C2H2_4	646..669	CDD:464025
		C2H2 Zn finger	648..669	CDD:275370
Btbd18	NP_001417674.1	None