Protein Alignment alphaTry and KLK4

DIOPT Version :9

• Sequence 1: NP_476771.1
• Gene: alphaTry / 48316
• FlyBaseID: FBgn0003863
• Length: 256
• Species: Drosophila melanogaster
• Sequence 2: NP_004908.4
• Gene: KLK4 / 9622
• HGNCID: 6365
• Length: 254
• Species: Homo sapiens
• Alignment Length: 251
• Identity: 80/251 - (31%)
• Similarity: 124/251 - (49%)
• Gaps: 12/251 - (4%)

  Fly     8 LSAVVCALGGTVPEGLLPQLDGRIVGGSATTISSFPWQISLQRSGSHSCGGSIYSANIIVTAAHC 72
            |..::..:.|::..|...|    |:.|...:..|.|||.:|.......|.|.:.....:::||||
Human    12 LGYLILGVAGSLVSGSCSQ----IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHC 72

  Fly    73 LQSVSASVLQVRAGSTYWSSGGVVAKVSSFKNHEGYNANTMVNDIAVIRLSSSLSFSSSIKAISL 137
            .|:.....|.:.:.......|..:.:.|....|..||...:.||:.:|:|..|:|.|.:|::||:
Human    73 FQNSYTIGLGLHSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISI 137

  Fly   138 ATYNPANGASAAVSGWGTQSSGSSSIPSQLQYVNVNIVSQSQCASSTYGYGSQIRNTMICAAA-- 200
            |:..|..|.|..|||||..::|  .:|:.||.|||::||:..|:..   |......:|.||..
Human   138 ASQCPTAGNSCLVSGWGLLANG--RMPTVLQCVNVSVVSEEVCSKL---YDPLYHPSMFCAGGGQ 197

  Fly   201 SGKDACQGDSGGPLVSGGVLVGVVSWGYG-CAYSNYPGVYADVAVLRSWVVSTANS 255
            ..||:|.|||||||:..|.|.|:||:|.. |.....||||.::.....|:..|..:
Human   198 DQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQA 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alphaTry	NP_476771.1	Tryp_SPc	30..249	CDD:214473	74/221 (33%)
KLK4	NP_004908.4	Tryp_SPc	31..250	CDD:238113	75/223 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D469244at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X21
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.920