Protein Alignment alphaTry and TMPRSS13

DIOPT Version :10

• Sequence 1: NP_476771.1
• Gene: alphaTry / 48316
• FlyBaseID: FBgn0003863
• Length: 256
• Species: Drosophila melanogaster
• Sequence 2: NP_001070731.1
• Gene: TMPRSS13 / 84000
• HGNCID: 29808
• Length: 567
• Species: Homo sapiens
• Alignment Length: 248
• Identity: 85/248 - (34%)
• Similarity: 126/248 - (50%)
• Gaps: 22/248 - (8%)

  Fly    24 LPQLDGRIVGGSATTISSFPWQISLQRSGSHSCGGSIYSANIIVTAAHCLQSVSASVLQ---VRA 85
            |..:.||||||:..:.|.:|||:||....:|.|||::..|..::|||||.......||:   |.|
Human   319 LRAMTGRIVGGALASDSKWPWQVSLHFGTTHICGGTLIDAQWVLTAAHCFFVTREKVLEGWKVYA 383

  Fly    86 GSTYWSSGGVVAKVSSFKNHEGYNANTMVNDIAVIRLSSSLSFSSSIKAISLATYNPANGASAA- 149
            |::........|.::....:..|.......|||::|||..|:.|:.|....|    |.:|.:.:
Human   384 GTSNLHQLPEAASIAEIIINSNYTDEEDDYDIALMRLSKPLTLSAHIHPACL----PMHGQTFSL 444

  Fly   150 -----VSGWG-TQSSGSSSIPSQLQYVNVNIVSQSQCASSTYGYGSQIRNTMICAA--ASGKDAC 206
                 ::|:| |:.:...:.|. |:.|.||::...:| :....|.|.:...|:||.  ..|:|:|
Human   445 NETCWITGFGKTRETDDKTSPF-LREVQVNLIDFKKC-NDYLVYDSYLTPRMMCAGDLRGGRDSC 507

  Fly   207 QGDSGGPLV----SGGVLVGVVSWGYGCAYSNYPGVYADVAVLRSWVVSTANS 255
            |||||||||    :...|.||.|||.||...|.||||..|..:..|:.|...|
Human   508 QGDSGGPLVCEQNNRWYLAGVTSWGTGCGQRNKPGVYTKVTEVLPWIYSKMES 560

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alphaTry	NP_476771.1	Tryp_SPc	30..249	CDD:214473	80/234 (34%)
TMPRSS13	NP_001070731.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..115
		PHA03378	<9..148	CDD:223065
		13 X 5 AA repeats of A-S-P-A-[GLQR]	9..93
		4 X 5 AA repeats of T-P-P-G-R	14..68
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	131..157
		SRCR_2	231..321	CDD:464747	1/1 (100%)
		Tryp_SPc	325..554	CDD:214473	80/234 (34%)