DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment alphaTry and prss60.1

DIOPT Version :9

Sequence 1:	NP_476771.1	Gene:	alphaTry / 48316	FlyBaseID:	FBgn0003863	Length:	256	Species:	Drosophila melanogaster
Sequence 2:	NP_001082915.1	Gene:	prss60.1 / 799770	ZFINID:	ZDB-GENE-070424-25	Length:	387	Species:	Danio rerio

Alignment Length:	270	Identity:	109/270 - (40%)
Similarity:	147/270 - (54%)	Gaps:	28/270 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 ILLSAVVCALGGTVPE---GLLPQLDGRIVGGSATTISSFPWQISLQRS--GSHSCGGSIYSANI 65
            :.|:.::|..|.....   ||.| |:.|||||......|:|||:||...  |.|.||||:.::..
Zfish     7 VSLALLLCVQGSHSQLNVCGLAP-LNNRIVGGVNAFDGSWPWQVSLHSPIYGGHFCGGSLINSEW 70

  Fly    66 IVTAAHCLQSVSASVLQVRAGSTYWSSGGVVA-----KVSSFKNHEGYNANTMVNDIAVIRLSSS 125
            ::||||||..::.|.|.|..|.|  :..||..     .||....|..||..|..||||::.|||:
Zfish    71 VLTAAHCLPRITTSSLLVFLGKT--TQQGVNTYEINRTVSVITVHPSYNNLTNENDIALLHLSSA 133

  Fly   126 LSFSSSIKAISLATYNPA--NGASAAVSGWGTQSSG-SSSIPSQLQYVNVNIVSQSQCASSTYGY 187
            ::||:.|:.:.||..|..  ||.|:.::|||....| :...|..||...:.:|...|| ::..|.
Zfish   134 VTFSNYIRPVCLAAQNSVFPNGTSSWITGWGNIQLGVNLPAPGILQETMIPVVPNDQC-NALLGS 197

  Fly   188 GSQIRNTMICAA--ASGKDACQGDSGGPLVSGGVLV----GVVSWGYGCAYSNYPGVYADVAVLR 246
            || :.|.||||.  ..|:|.||||||||:||...||    |:.|||||||....||||..|:..:
Zfish   198 GS-VTNNMICAGLLQGGRDTCQGDSGGPMVSKQCLVWVQSGITSWGYGCADPYSPGVYTRVSQYQ 261

  Fly   247 SWVVSTANSI 256
            ||:    |||
Zfish   262 SWI----NSI 267

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
alphaTry	NP_476771.1	Tryp_SPc	30..249	CDD:214473	98/234 (42%)
prss60.1	NP_001082915.1	Tryp_SPc	33..264	CDD:214473	98/234 (42%)
		Tryp_SPc	34..267	CDD:238113	99/240 (41%)
		Somatomedin_B	349..382	CDD:295334
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910