DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment alphaTry and f7

DIOPT Version :9

Sequence 1:	NP_476771.1	Gene:	alphaTry / 48316	FlyBaseID:	FBgn0003863	Length:	256	Species:	Drosophila melanogaster
Sequence 2:	NP_001072819.1	Gene:	f7 / 780280	XenbaseID:	XB-GENE-5787186	Length:	452	Species:	Xenopus tropicalis

Alignment Length:	253	Identity:	80/253 - (31%)
Similarity:	117/253 - (46%)	Gaps:	29/253 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 PEGLLPQLD-----GRIVGGSATTISSFPWQISLQRSGSHSCGGSIYSANIIVTAAHCLQSVSAS 79
            |.|.:|.|.     .|||||........|||..|..:....|||::.:.|.::||||||:.:..:
Frog   196 PCGKIPVLKNVNKRARIVGGDMCPKGECPWQALLMYNEIFICGGTLIAPNWVITAAHCLKPLPEN 260

  Fly    80 VLQV-----RAGSTYWSSGGVVAKVSSFKNHEGY--NANTMVNDIAVIRLSSSLSFSSSIKAISL 137
            .|.|     |.|:...:.  ..:|||....||.|  :.....||||:::|::.::::..:..:.|
Frog   261 KLTVVLGEHRIGTPEGTE--QESKVSKIIMHEHYYGSKTNNDNDIALLKLTTPVNYTDYVVPLCL 323

  Fly   138 -----ATYNPANGASAAVSGWGTQSSGSSSIPSQLQYVNVNIVSQSQCASSTYGYGSQIRNTMIC 197
                 |.....:...:.||||| :...|.:.|..||.|.:..|....|...|.   ..|...|.|
Frog   324 PEKQFAVQELLSIRYSTVSGWG-RLLESGATPELLQRVQLPRVKTQDCIRQTQ---MNISQNMFC 384

  Fly   198 AAAS--GKDACQGDSGGP----LVSGGVLVGVVSWGYGCAYSNYPGVYADVAVLRSWV 249
            |..:  .||:|:||||||    ..:...|.|:||||.|||.....|||..|:....|:
Frog   385 AGYTDGSKDSCKGDSGGPHATQYKNTHFLTGIVSWGLGCAKKEKYGVYTRVSRYTEWI 442

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
alphaTry	NP_476771.1	Tryp_SPc	30..249	CDD:214473	75/236 (32%)
f7	NP_001072819.1	Gla	67..107	CDD:366184
		EGF_CA	108..144	CDD:238011
		FXa_inhibition	153..189	CDD:373209
		Tryp_SPc	212..445	CDD:238113	75/237 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910