Protein Alignment alphaTry and TPSAB1

DIOPT Version :10

• Sequence 1: NP_476771.1
• Gene: alphaTry / 48316
• FlyBaseID: FBgn0003863
• Length: 256
• Species: Drosophila melanogaster
• Sequence 2: NP_003285.2
• Gene: TPSAB1 / 7177
• HGNCID: 12019
• Length: 275
• Species: Homo sapiens
• Alignment Length: 273
• Identity: 90/273 - (32%)
• Similarity: 134/273 - (49%)
• Gaps: 30/273 - (10%)

  Fly     1 MLKIVILLSAVVCALGGTVP-EGLLPQLDGRIVGGSATTISSFPWQISLQRSG---SHSCGGSIY 61
            ||.:::|...|:.:.....| .|...|..| ||||.....|.:|||:||:..|   .|.||||:.
Human     1 MLNLLLLALPVLASRAYAAPAPGQALQRVG-IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLI 64

  Fly    62 SANIIVTAAHC----LQSVSASVLQVRAGSTYWSSGGVVAKVSSFKNHEGYNANTMVNDIAVIRL 122
            ....::|||||    ::.::|..:|:|....|:..  .:..||....|..:....:..|||::.|
Human    65 HPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQD--QLLPVSRIIVHPQFYTAQIGADIALLEL 127

  Fly   123 SSSLSFSSSIKAISL----ATYNPANGASAAVSGWG-TQSSGSSSIPSQLQYVNVNIVSQSQCAS 182
            ...::.||.:..::|    .|:.|  |....|:||| ..:......|..|:.|.|.|:....| .
Human   128 EEPVNVSSHVHTVTLPPASETFPP--GMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHIC-D 189

  Fly   183 STYGYGSQ-------IRNTMICAAASGKDACQGDSGGPL---VSGGVL-VGVVSWGYGCAYSNYP 236
            :.|..|:.       :|:.|:||..:.:|:|||||||||   |:|..| .||||||.|||..|.|
Human   190 AKYHLGAYTGDDVRIVRDDMLCAGNTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRP 254

  Fly   237 GVYADVAVLRSWV 249
            |:|..|.....|:
Human   255 GIYTRVTYYLDWI 267

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alphaTry	NP_476771.1	Tryp_SPc	30..249	CDD:214473	81/241 (34%)
TPSAB1	NP_003285.2	Tryp_SPc	31..268	CDD:238113	82/242 (34%)