Protein Alignment alphaTry and PRSS22

DIOPT Version :10

• Sequence 1: NP_476771.1
• Gene: alphaTry / 48316
• FlyBaseID: FBgn0003863
• Length: 256
• Species: Drosophila melanogaster
• Sequence 2: XP_054169579.1
• Gene: PRSS22 / 64063
• HGNCID: 14368
• Length: 425
• Species: Homo sapiens
• Alignment Length: 274
• Identity: 94/274 - (34%)
• Similarity: 133/274 - (48%)
• Gaps: 52/274 - (18%)

  Fly    17 GTVPEGLL-------------PQLDGRIVGGSATTISSFPWQISLQRSGSHSCGGSIYSANIIVT 68
            |:.|..:|             ||...|:|||..:|.|.:||.:|:|::|:|.|.||:.::..::|
Human   131 GSSPPAILNAARIPVPPACGKPQQLNRVVGGEDSTDSEWPWIVSIQKNGTHHCAGSLLTSRWVIT 195

  Fly    69 AAHCLQS--VSASVLQVRAGSTYWSSGGVVAK-------------VSSFKNHEGYNANTMVNDIA 118
            ||||.:.  ....:..|..|:  |..|...::             |.|:|  ||..|     |||
Human   196 AAHCFKDNLNKPYLFSVLLGA--WQLGNPGSRSQKVGVAWVEPHPVYSWK--EGACA-----DIA 251

  Fly   119 VIRLSSSLSFSSSIKAISL---ATYNPANGASAAVSGWGTQSSG-SSSIPSQLQYVNVNIVSQSQ 179
            ::||..|:.||..:..|.|   :.:.|.| ....:||||:...| ....|..||.:.|.|:....
Human   252 LVRLERSIQFSERVLPICLPDASIHLPPN-THCWISGWGSIQDGVPLPHPQTLQKLKVPIIDSEV 315

  Fly   180 CASSTYGYGS---QIRNTMICAA--ASGKDACQGDSGGPL---VSGG-VLVGVVSWGYGCAYSNY 235
            | |..|..|:   .|...|:||.  ...:|||.|||||||   |.|. :|.|::|||.|||..|.
Human   316 C-SHLYWRGAGQGPITEDMLCAGYLEGERDACLGDSGGPLMCQVDGAWLLAGIISWGEGCAERNR 379

  Fly   236 PGVYADVAVLRSWV 249
            ||||..::..||||
Human   380 PGVYISLSAHRSWV 393

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alphaTry	NP_476771.1	Tryp_SPc	30..249	CDD:214473	87/246 (35%)
PRSS22	XP_054169579.1	Tryp_SPc	158..396	CDD:238113	88/247 (36%)