Protein Alignment alphaTry and PRSS22

DIOPT Version :9

• Sequence 1: NP_476771.1
• Gene: alphaTry / 48316
• FlyBaseID: FBgn0003863
• Length: 256
• Species: Drosophila melanogaster
• Sequence 2: NP_071402.1
• Gene: PRSS22 / 64063
• HGNCID: 14368
• Length: 317
• Species: Homo sapiens
• Alignment Length: 275
• Identity: 95/275 - (34%)
• Similarity: 138/275 - (50%)
• Gaps: 40/275 - (14%)

  Fly     4 IVILLSAVVCALGGTVPEGL-LPQLDGRIVGGSATTISSFPWQISLQRSGSHSCGGSIYSANIIV 67
            :::..:|::.|....||... .||...|:|||..:|.|.:||.:|:|::|:|.|.||:.::..::
Human    22 LLLASTAILNAARIPVPPACGKPQQLNRVVGGEDSTDSEWPWIVSIQKNGTHHCAGSLLTSRWVI 86

  Fly    68 TAAHCLQS--VSASVLQVRAGSTYWSSGGVVAK-------------VSSFKNHEGYNANTMVNDI 117
            |||||.:.  ....:..|..|:  |..|...::             |.|:|  ||..|     ||
Human    87 TAAHCFKDNLNKPYLFSVLLGA--WQLGNPGSRSQKVGVAWVEPHPVYSWK--EGACA-----DI 142

  Fly   118 AVIRLSSSLSFSSSIKAISL---ATYNPANGASAAVSGWGTQSSG-SSSIPSQLQYVNVNIVSQS 178
            |::||..|:.||..:..|.|   :.:.|.| ....:||||:...| ....|..||.:.|.|:...
Human   143 ALVRLERSIQFSERVLPICLPDASIHLPPN-THCWISGWGSIQDGVPLPHPQTLQKLKVPIIDSE 206

  Fly   179 QCASSTYGYGS---QIRNTMICAA--ASGKDACQGDSGGPL---VSGG-VLVGVVSWGYGCAYSN 234
            .| |..|..|:   .|...|:||.  ...:|||.|||||||   |.|. :|.|::|||.|||..|
Human   207 VC-SHLYWRGAGQGPITEDMLCAGYLEGERDACLGDSGGPLMCQVDGAWLLAGIISWGEGCAERN 270

  Fly   235 YPGVYADVAVLRSWV 249
            .||||..::..||||
Human   271 RPGVYISLSAHRSWV 285

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alphaTry	NP_476771.1	Tryp_SPc	30..249	CDD:214473	87/246 (35%)
PRSS22	NP_071402.1	Tryp_SPc	50..288	CDD:238113	88/247 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	157	1.000	Inparanoid score	I4288
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.960