DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment alphaTry and AgaP_AGAP011918

DIOPT Version :9

Sequence 1:	NP_476771.1	Gene:	alphaTry / 48316	FlyBaseID:	FBgn0003863	Length:	256	Species:	Drosophila melanogaster
Sequence 2:	XP_001689276.1	Gene:	AgaP_AGAP011918 / 5667954	VectorBaseID:	AGAP011918	Length:	259	Species:	Anopheles gambiae

Alignment Length:	252	Identity:	89/252 - (35%)
Similarity:	132/252 - (52%)	Gaps:	13/252 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 IVILLSAVVCALGGTVPEGLLPQLD--GRIVGGSATTISSFPWQISL-QRSGSHSCGGSIYSANI 65
            :|:.:::|.|.     .:..|...|  ||||.|.......||:|:|| ..:..|.|||:|...:.
Mosquito     8 VVLCVASVACG-----EDAALRTADWEGRIVNGLNAVSGQFPYQVSLTSATYQHFCGGAIIGNHW 67

  Fly    66 IVTAAHCLQSVSASVLQVRAGSTYWSSGGVVAKVSSFKNHEGYNANTMVNDIAVIRLSSSLSFSS 130
            |:||||||.....:.:....|:...:.||....|..|..|..:|..|..||||::|...|:||::
Mosquito    68 ILTAAHCLTGRKPAEVIAVVGALTSARGGYNYDVEQFILHPNFNEWTQQNDIALVRTKWSISFNT 132

  Fly   131 SIKAISLA-TYNPANGASAAVSGWGTQSSGSSSIPSQLQYVNVNIVSQSQCASSTYGYGSQ-IRN 193
            ::..:.:| ||.|||.|..| ||||..:........:||||.:..:|...|:.......:: |..
Mosquito   133 AVFPVKMARTYTPANRAVLA-SGWGLTTLSVPKPADRLQYVALRTISNEDCSERFRKLQNRAITP 196

  Fly   194 TMICA-AASGKDACQGDSGGPLVSGGVLVGVVSWGYGCAYSNYPGVYADVAVLRSWV 249
            :::|. :.:.:..|.||||||||..|.|||:||||..||. .||.||..|:..|:|:
Mosquito   197 SILCTFSRNEQGTCMGDSGGPLVEDGELVGIVSWGIPCAV-GYPDVYVRVSSFRAWI 252

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
alphaTry	NP_476771.1	Tryp_SPc	30..249	CDD:214473	82/222 (37%)
AgaP_AGAP011918	XP_001689276.1	Tryp_SPc	31..252	CDD:214473	82/222 (37%)
AgaP_AGAP011918	XP_001689276.1	Tryp_SPc	32..252	CDD:238113	81/221 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG25816
OrthoDB	1	1.010	-	-		D469244at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.930