DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment alphaTry and AgaP_AGAP001250

DIOPT Version :9

Sequence 1:	NP_476771.1	Gene:	alphaTry / 48316	FlyBaseID:	FBgn0003863	Length:	256	Species:	Drosophila melanogaster
Sequence 2:	XP_001689374.2	Gene:	AgaP_AGAP001250 / 5667664	VectorBaseID:	AGAP001250	Length:	279	Species:	Anopheles gambiae

Alignment Length:	241	Identity:	87/241 - (36%)
Similarity:	133/241 - (55%)	Gaps:	15/241 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 GGTVPEGLLPQLDGRIVGGSATTISSFPWQISLQRSGSHSCGGSIYSANIIVTAAHCLQSV-SAS 79
            ||...:|    ...|||||....|.:||:|:||:|||.|:||.|:.|....::||||...: ..:
Mosquito    43 GGASHDG----KSARIVGGRDAPIENFPYQLSLRRSGVHACGASVISLRWALSAAHCTYPIPQMN 103

  Fly    80 VLQVRAGSTYWSSGGVVAKVSSFKNHEGYNANTMVNDIAVIRLSSSLSFSSSIKAISL--ATYNP 142
            .:.:||||:...:||.:..::...||..::..|:..|:.|::.|:.: ....|..:.|  ||...
Mosquito   104 EMSLRAGSSNRLAGGTIIPITQIINHPLFSEYTIEYDVCVLQTSTEM-VGQFIVPVVLPPATSGF 167

  Fly   143 ANGASAAVSGWGTQSSGSSSIPSQLQYVNVNIVSQSQCASSTYGYGSQ-IRNTMICAAASGKDAC 206
            |.|..|..:|||..:. ..|:|.|||||.:.::|..||.:|   :.|: |...|:||...|:|.|
Mosquito   168 APGTMANATGWGLLNV-PGSLPVQLQYVALPLISLDQCRNS---WPSEWITEEMLCAGQPGRDTC 228

  Fly   207 QGDSGGPLVSGGVLVGVVSWGYGCAYSNYPGVYADVA--VLRSWVV 250
            .||||||||..|..:|:.|||......|.|.|:|:.|  .:||:::
Mosquito   229 GGDSGGPLVINGYQMGIASWGVSECSGNLPSVFANTANPTVRSFIL 274

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
alphaTry	NP_476771.1	Tryp_SPc	30..249	CDD:214473	84/224 (38%)
AgaP_AGAP001250	XP_001689374.2	Tryp_SPc	53..273	CDD:214473	84/224 (38%)
AgaP_AGAP001250	XP_001689374.2	Tryp_SPc	54..273	CDD:238113	83/223 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BBP0
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG25816
OrthoDB	1	1.010	-	-		D469244at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	5	4.790