DRSC/TRiP Functional Genomics Resources

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Protein Alignment alphaTry and KLK7

DIOPT Version :9

Sequence 1:NP_476771.1 Gene:alphaTry / 48316 FlyBaseID:FBgn0003863 Length:256 Species:Drosophila melanogaster
Sequence 2:NP_005037.1 Gene:KLK7 / 5650 HGNCID:6368 Length:253 Species:Homo sapiens


Alignment Length:256 Identity:89/256 - (34%)
Similarity:126/256 - (49%) Gaps:17/256 - (6%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MLKIVILLSAVVCALGGTVPEGLLPQLDGRIVGGSATTISSFPWQISLQRSGSHSCGGSIYSANI 65
            :|.:.|||.::.....|...:|      .:|:.|:.....|.|||::|.......|||.:.:...
Human     6 LLPLQILLLSLALETAGEEAQG------DKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERW 64

  Fly    66 IVTAAHCLQSVSASVLQVRAGS-TYWSSGGVVAKVSSFKNHEGYNANTMVNDIAVIRLSSSLSFS 129
            ::|||||    ..:...|..|| |.........|.|....|.||:..|.|||:.:::|:|....|
Human    65 VLTAAHC----KMNEYTVHLGSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLS 125

  Fly   130 SSIKAISLATYNPANGASAAVSGWGTQSSGSSSIPSQLQYVNVNIVSQSQCASSTYGYGSQIRNT 194
            |.:|.:.|.:.....|.:..||||||.:|...:.||.|..|:|.::|...|   |..|...:.|:
Human   126 SMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDC---TKVYKDLLENS 187

  Fly   195 MICAAA--SGKDACQGDSGGPLVSGGVLVGVVSWG-YGCAYSNYPGVYADVAVLRSWVVST 252
            |:||..  |.|:||.||||||||..|.|.|:|||| :.|...|.||||..|.....|:..|
Human   188 MLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDT 248

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
alphaTryNP_476771.1 Tryp_SPc 30..249 CDD:214473 81/222 (36%)
KLK7NP_005037.1 Tryp_SPc 29..245 CDD:214473 81/222 (36%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X21
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.910

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