DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment alphaTry and tmprss9

DIOPT Version :9

Sequence 1:	NP_476771.1	Gene:	alphaTry / 48316	FlyBaseID:	FBgn0003863	Length:	256	Species:	Drosophila melanogaster
Sequence 2:	XP_021325244.1	Gene:	tmprss9 / 562051	ZFINID:	ZDB-GENE-050208-573	Length:	788	Species:	Danio rerio

Alignment Length:	252	Identity:	90/252 - (35%)
Similarity:	128/252 - (50%)	Gaps:	32/252 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 GLLPQLDGRIVGGSATTISSFPWQISLQRSGSHSCGGSIYSANIIVTAAHCLQSVSASVLQVRAG 86
            |..|.:..|||||..|....||||:||:..|.|:||.||.::..:|:||||        .:|...
Zfish   223 GTRPVMSNRIVGGENTRHGEFPWQVSLRLRGRHTCGASIVNSRWLVSAAHC--------FEVENN 279

  Fly    87 STYWS--------SG----GVVAKVSSFKNHEGYNANTMVNDIAVIRLSSSLSFSSSIKAISLAT 139
            ...|:        ||    ..:..:.|......|:..|..:|:.|:.|.:.|.||..::.:.:.:
Zfish   280 PKDWTALVGANQVSGAEAEAFIVNIKSLVMSPKYDPMTTDSDVTVLELETPLKFSHYVQPVCIPS 344

  Fly   140 ----YNPANGASAAVSGWGTQSSGSSSIPSQLQYVNVNIVSQSQCASSTYGYGSQIRNTMICAAA 200
                :.|  |.:..|||||..:..::.:||.||...|.|:....|..|:...|:..:|.|.....
Zfish   345 SSHVFTP--GQNCIVSGWGALNQYTTEVPSTLQKAIVKIIDSKVCNKSSVYRGALTQNMMCAGFL 407

  Fly   201 SGK-DACQGDSGGPL---VSGG--VLVGVVSWGYGCAYSNYPGVYADVAVLRSWVVS 251
            .|| |:|||||||||   |:.|  .|.|:||||.|||..|.||||:.|..||:|:||
Zfish   408 QGKVDSCQGDSGGPLACEVAAGRYFLAGIVSWGVGCAQINKPGVYSRVTKLRNWIVS 464

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
alphaTry	NP_476771.1	Tryp_SPc	30..249	CDD:214473	85/240 (35%)
tmprss9	XP_021325244.1	SEA	52..146	CDD:307516
		LDLa	185..220	CDD:238060
		Tryp_SPc	232..462	CDD:238113	84/239 (35%)
		LDLa	510..544	CDD:238060
		Tryp_SPc	557..783	CDD:238113
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910