DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment alphaTry and Cfd

DIOPT Version :9

Sequence 1:	NP_476771.1	Gene:	alphaTry / 48316	FlyBaseID:	FBgn0003863	Length:	256	Species:	Drosophila melanogaster
Sequence 2:	NP_001071110.1	Gene:	Cfd / 54249	RGDID:	2498	Length:	263	Species:	Rattus norvegicus

Alignment Length:	257	Identity:	80/257 - (31%)
Similarity:	129/257 - (50%)	Gaps:	23/257 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LKIVILLSAVVCALGGTVPEGLLPQLDGRIVGGSATTISSFPWQISLQRSGSHSCGGSIYSANII 66
            |..:::|.|.||          :.|..|||:||......:.|:..|:|.:|:|.|||::.....:
  Rat     7 LVALVVLEAAVC----------VAQPRGRILGGQEAMAHARPYMASVQVNGTHVCGGTLVDEQWV 61

  Fly    67 VTAAHCLQSVSA-SVLQVRAGSTYWSSGGV---VAKVSSFKNHEGYNANTMVNDIAVIRLSSSLS 127
            ::||||:..|:. .|:||..|:...||...   :..|.|...|.|...:::.:|:.:.:||.:.|
  Rat    62 LSAAHCMDGVTKDEVVQVLLGAHSLSSPEPYKHLYDVQSVVLHPGSRPDSVEDDLMLFKLSHNAS 126

  Fly   128 FSSSIKAISL----ATYNPANGASAAVSGWGTQSSGSSSIPSQLQYVNVNIVSQSQCASSTYGYG 188
            ....::.:.|    ....|  |....|:|||..:..... |..||.:.|:|:.::.|...||..|
  Rat   127 LGPHVRPLPLQREDREVKP--GTLCDVAGWGVVTHAGRR-PDVLQQLTVSIMDRNTCNLRTYHDG 188

  Fly   189 SQIRNTMICAAASGKDACQGDSGGPLVSGGVLVGVVSWGYG-CAYSNYPGVYADVAVLRSWV 249
            :..:| |:||.::.:|.|:||||||||.|..:..||:||.. |.....|||:..||....|:
  Rat   189 AITKN-MMCAESNRRDTCRGDSGGPLVCGDAVEAVVTWGSRVCGNRRKPGVFTRVATYVPWI 249

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
alphaTry	NP_476771.1	Tryp_SPc	30..249	CDD:214473	72/227 (32%)
Cfd	NP_001071110.1	Tryp_SPc	26..252	CDD:238113	72/228 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X21
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910