Protein Alignment alphaTry and Cfd

DIOPT Version :10

• Sequence 1: NP_476771.1
• Gene: alphaTry / 48316
• FlyBaseID: FBgn0003863
• Length: 256
• Species: Drosophila melanogaster
• Sequence 2: NP_001071110.1
• Gene: Cfd / 54249
• RGDID: 2498
• Length: 263
• Species: Rattus norvegicus
• Alignment Length: 257
• Identity: 80/257 - (31%)
• Similarity: 129/257 - (50%)
• Gaps: 23/257 - (8%)

  Fly     2 LKIVILLSAVVCALGGTVPEGLLPQLDGRIVGGSATTISSFPWQISLQRSGSHSCGGSIYSANII 66
            |..:::|.|.||          :.|..|||:||......:.|:..|:|.:|:|.|||::.....:
  Rat     7 LVALVVLEAAVC----------VAQPRGRILGGQEAMAHARPYMASVQVNGTHVCGGTLVDEQWV 61

  Fly    67 VTAAHCLQSVSA-SVLQVRAGSTYWSSGGV---VAKVSSFKNHEGYNANTMVNDIAVIRLSSSLS 127
            ::||||:..|:. .|:||..|:...||...   :..|.|...|.|...:::.:|:.:.:||.:.|
  Rat    62 LSAAHCMDGVTKDEVVQVLLGAHSLSSPEPYKHLYDVQSVVLHPGSRPDSVEDDLMLFKLSHNAS 126

  Fly   128 FSSSIKAISL----ATYNPANGASAAVSGWGTQSSGSSSIPSQLQYVNVNIVSQSQCASSTYGYG 188
            ....::.:.|    ....|  |....|:|||..:..... |..||.:.|:|:.::.|...||..|
  Rat   127 LGPHVRPLPLQREDREVKP--GTLCDVAGWGVVTHAGRR-PDVLQQLTVSIMDRNTCNLRTYHDG 188

  Fly   189 SQIRNTMICAAASGKDACQGDSGGPLVSGGVLVGVVSWGYG-CAYSNYPGVYADVAVLRSWV 249
            :..:| |:||.::.:|.|:||||||||.|..:..||:||.. |.....|||:..||....|:
  Rat   189 AITKN-MMCAESNRRDTCRGDSGGPLVCGDAVEAVVTWGSRVCGNRRKPGVFTRVATYVPWI 249

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alphaTry	NP_476771.1	Tryp_SPc	30..249	CDD:214473	72/227 (32%)
Cfd	NP_001071110.1	Tryp_SPc	26..252	CDD:238113	72/228 (32%)
		Self-inhibitor loop. /evidence=ECO:0000250|UniProtKB:P00746	224..228		2/3 (67%)