DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment alphaTry and Prss44

DIOPT Version :9

Sequence 1:	NP_476771.1	Gene:	alphaTry / 48316	FlyBaseID:	FBgn0003863	Length:	256	Species:	Drosophila melanogaster
Sequence 2:	XP_008764869.1	Gene:	Prss44 / 501060	RGDID:	1560940	Length:	373	Species:	Rattus norvegicus

Alignment Length:	234	Identity:	82/234 - (35%)
Similarity:	125/234 - (53%)	Gaps:	16/234 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 RIVGGSATTISSFPWQISLQRSGSHSCGGSIYSANIIVTAAHCLQSVSASVLQVRAGSTYWSSGG 94
            |||||....|..:|||:|||....|.||||:.|...::|||||:......|:.: ..:..|||..
  Rat   112 RIVGGKPAPIRKWPWQVSLQVHKQHICGGSLISKWWVMTAAHCVYGHLDYVVSM-GEADLWSSMS 175

  Fly    95 VVAKVSSFKNHEGYNA-NTMVNDIAVIRLSSSLSFSSSIKAISL--ATYNPANGASAAVSGWG-T 155
            |...|.....|:.|:. .|:|:|||::.|:..:::|.:|:.:.:  .::....|....|:||| |
  Rat   176 VKIPVQDIIVHQDYSVMRTIVHDIALVLLAFPVNYSVNIQPVCIPEKSFLVQPGTLCWVTGWGKT 240

  Fly   156 QSSGSSSIPSQLQYVNVNIVSQSQC----ASSTYGYGSQIRNTMICA-AASGKDACQGDSGGPLV 215
            ...|.||  ..|:.|:::|:...:|    ...|....:.::...:|. ...|.||||||||||:|
  Rat   241 IERGRSS--RVLREVDLSIIRHERCNQILKDITGRIFTLVQEGGVCGYNKKGGDACQGDSGGPMV 303

  Fly   216 ----SGGVLVGVVSWGYGCAYSNYPGVYADVAVLRSWVV 250
                ...|.||:||||.||....|||:|.:|:..|.|::
  Rat   304 CEFNKTWVQVGIVSWGLGCGRIGYPGIYTEVSYYRDWII 342

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
alphaTry	NP_476771.1	Tryp_SPc	30..249	CDD:214473	81/231 (35%)
Prss44	XP_008764869.1	Tryp_SPc	112..341	CDD:214473	81/231 (35%)
Prss44	XP_008764869.1	Tryp_SPc	113..341	CDD:238113	80/230 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910