DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment alphaTry and prss27

DIOPT Version :9

Sequence 1:	NP_476771.1	Gene:	alphaTry / 48316	FlyBaseID:	FBgn0003863	Length:	256	Species:	Drosophila melanogaster
Sequence 2:	XP_031749235.1	Gene:	prss27 / 496619	XenbaseID:	XB-GENE-5744470	Length:	724	Species:	Xenopus tropicalis

Alignment Length:	294	Identity:	107/294 - (36%)
Similarity:	143/294 - (48%)	Gaps:	43/294 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MLKIVILLSA--VVCALGGTVPEGLLPQLDGRIVGGSATTISSFPWQISLQRSGSHSCGGSIYSA 63
            ||:|:.||.|  .|.|:.....:   |....|||||:......:|||:|:....||.||||:.|:
Frog   391 MLRIISLLLAGFAVTAISTGCGQ---PAFSDRIVGGNNAVFGEWPWQVSIVYQNSHICGGSLVSS 452

  Fly    64 NIIVTAAHCL-QSVSASVLQVRAGS---TYWSSGGVVAKVSSFKNHEGYNANTMVNDIAVIRLSS 124
            |.:|:||||. :|.....:||..|.   ...:|..|:.:|.....:..|.......|||::.:.|
Frog   453 NWVVSAAHCFPRSYKIENMQVLLGCFALMNLTSDAVIIRVKRVITYPLYTGEGSSGDIAMVEMES 517

  Fly   125 SLSFSSSIKAISLATYNP--ANGASAAVSGWGT-QSSGSSSIPSQLQYVNVNIVSQSQCASSTYG 186
            .:::||.|..|.:...|.  .:|....|:|||. ||..|.|.|..||.|.|.:|:.|.| .:.|.
Frog   518 PVTYSSYILPICIPLTNEDFPSGKMCWVTGWGNIQSDVSLSPPYPLQEVEVPLVNASSC-DTMYH 581

  Fly   187 YGSQ-------IRNTMICAA--ASGKDACQGDSGGPLV--SGG--VLVGVVSWGYGCAYSNYPGV 238
            |.|.       :.:.||||.  ...||||||||||||.  ||.  .|.|:||||.|||..|.|||
Frog   582 YNSDLNPATQLVHDDMICAGYPEGQKDACQGDSGGPLACKSGNYWFLTGIVSWGDGCAQPNRPGV 646

  Fly   239 YADVAVLRSWV-----------------VSTANS 255
            |..|:...||:                 :|.|||
Frog   647 YTKVSSFSSWINQYLVLNVSVTTKTPHSISLANS 680

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
alphaTry	NP_476771.1	Tryp_SPc	30..249	CDD:214473	93/238 (39%)
prss27	XP_031749235.1	Tryp_SPc	34..271	CDD:238113
prss27	XP_031749235.1	Tryp_SPc	420..659	CDD:238113	93/239 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910