Protein Alignment alphaTry and CTRB2

DIOPT Version :10

• Sequence 1: NP_476771.1
• Gene: alphaTry / 48316
• FlyBaseID: FBgn0003863
• Length: 256
• Species: Drosophila melanogaster
• Sequence 2: NP_001020371.3
• Gene: CTRB2 / 440387
• HGNCID: 2522
• Length: 263
• Species: Homo sapiens
• Alignment Length: 266
• Identity: 102/266 - (38%)
• Similarity: 143/266 - (53%)
• Gaps: 38/266 - (14%)

  Fly    14 ALGGT-----VPEGLLPQLDG--RIVGGSATTISSFPWQISLQ-RSGSHSCGGSIYSANIIVTAA 70
            ||.||     || .:.|.|.|  |||.|......|:|||:||| ::|.|.||||:.|.:.:||||
Human    11 ALLGTTFGCGVP-AIHPVLSGLSRIVNGEDAVPGSWPWQVSLQDKTGFHFCGGSLISEDWVVTAA 74

  Fly    71 HCLQSVSASVLQVRAGSTYWSSGG--------VVAKVSSFKNHEGYNANTMVNDIAVIRLSSSLS 127
            ||....|..|:   ||.  :..|.        .:|||  |||.: ::..|:.|||.:::|::...
Human    75 HCGVRTSDVVV---AGE--FDQGSDEENIQVLKIAKV--FKNPK-FSILTVNNDITLLKLATPAR 131

  Fly   128 FSSSIKAISLATYN---PANGASAAVSGWGTQSSGSSSIPSQLQYVNVNIVSQSQCASSTYGYGS 189
            ||.::.|:.|.:.:   || |...|.:|||.....::..|.:||...:.::|.::|..|   :|.
Human   132 FSQTVSAVCLPSADDDFPA-GTLCATTGWGKTKYNANKTPDKLQQAALPLLSNAECKKS---WGR 192

  Fly   190 QIRNTMICAAASGKDACQGDSGGPLV----SGGVLVGVVSWGYGCAYSNYPGVYADVAVLRSWV- 249
            :|.:.||||.|||..:|.||||||||    ....|||:||||.....:..|.|||.||.|..||
Human   193 RITDVMICAGASGVSSCMGDSGGPLVCQKDGAWTLVGIVSWGSRTCSTTTPAVYARVAKLIPWVQ 257

  Fly   250 -VSTAN 254
             :..||
Human   258 KILAAN 263

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alphaTry	NP_476771.1	Tryp_SPc	30..249	CDD:214473	89/234 (38%)
CTRB2	NP_001020371.3	Tryp_SPc	34..259	CDD:238113	90/236 (38%)