DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment alphaTry and AgaP_AGAP012778

DIOPT Version :9

Sequence 1:	NP_476771.1	Gene:	alphaTry / 48316	FlyBaseID:	FBgn0003863	Length:	256	Species:	Drosophila melanogaster
Sequence 2:	XP_001230340.2	Gene:	AgaP_AGAP012778 / 4397620	VectorBaseID:	AGAP012778	Length:	276	Species:	Anopheles gambiae

Alignment Length:	257	Identity:	70/257 - (27%)
Similarity:	115/257 - (44%)	Gaps:	32/257 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 LLP---QLDG---RIVGGSATTISSFPWQIS----LQRSGSHSCGGSIYSANIIVTAAHCLQSVS 77
            |||   |.|.   ||:||||.|..|  |.::    :..:.|:.|||::.....::|||||:.:..
Mosquito    29 LLPLAVQADAGSQRIIGGSAVTAPS--WMVAVGEVVNGNWSNFCGGTLIDKQWVLTAAHCVANAQ 91

  Fly    78 ASVLQVRAGSTYWSSGGVVAKVSSFKNHEGYNANTMVN----------DIAVIRLSSSLSFSSSI 132
            :..::|..|.:..|.....:||.....|..|..|.:.|          |:|::.|::.::.:..:
Mosquito    92 SGPMEVAIGVSDLSRPHTRSKVDQVLMHPEYYVNLLSNLGYRETPYSSDVALLHLATPVTQAPIV 156

  Fly   133 KA--ISLATYNPANGASAAVSGWGTQSSGSSSIPSQLQYVNVNIVSQSQCASSTYGYGSQIRNTM 195
            .|  .:..|:........|:...|.....:.|.|   |.:.|::..:.:   ..|.||......:
Mosquito   157 MADITTKDTWQWNTTMLHAIGYGGINPDATKSSP---QLLAVDLAYRGE---RDYWYGDPTTTHI 215

  Fly   196 ICAAASGKDACQGDSGGPLVSGGVLVGVVSWG-YGCAYSNYPGVYADVAVLRSWVVSTANSI 256
            .....:|:|.|:|||||||..||.||||.|:| :.|| :...|.|........|:|.....:
Mosquito   216 FAGKLAGQDTCKGDSGGPLTYGGKLVGVTSYGAFPCA-TGSAGGYTYAPAFSDWIVGQQQGV 276

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
alphaTry	NP_476771.1	Tryp_SPc	30..249	CDD:214473	63/235 (27%)
AgaP_AGAP012778	XP_001230340.2	Tryp_SPc	42..269	CDD:214473	63/235 (27%)
AgaP_AGAP012778	XP_001230340.2	Tryp_SPc	43..269	CDD:238113	62/234 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24276
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100