Protein Alignment alphaTry and KLK12

DIOPT Version :9

• Sequence 1: NP_476771.1
• Gene: alphaTry / 48316
• FlyBaseID: FBgn0003863
• Length: 256
• Species: Drosophila melanogaster
• Sequence 2: NP_062544.1
• Gene: KLK12 / 43849
• HGNCID: 6360
• Length: 254
• Species: Homo sapiens
• Alignment Length: 255
• Identity: 89/255 - (34%)
• Similarity: 124/255 - (48%)
• Gaps: 43/255 - (16%)

  Fly     2 LKIVILLSAVVCALGGTVPEGLLPQLDGRIVGGSATTISSFPWQISLQRSGSHSCGGSIYSANII 66
            |.|.:||    |.||  :.:...|    :|..|:....:|.|||:.|....|..|||.:.....:
Human     3 LSIFLLL----CVLG--LSQAATP----KIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWV 57

  Fly    67 VTAAHCLQSVSASVLQVRAGSTYWSSGGVVA----------KVSSFK-NHEGY-NANTM-VNDIA 118
            :|||||            :||.||...|..:          :.|.|. .|.|| .|:|. .:|:.
Human    58 LTAAHC------------SGSRYWVRLGEHSLSQLDWTEQIRHSGFSVTHPGYLGASTSHEHDLR 110

  Fly   119 VIRLSSSLSFSSSIKAISLATYNPANGASAAVSGWGTQSSGSSSIPSQLQYVNVNIVSQSQCASS 183
            ::||...:..:||::.:.|.......|....|||||..:...:..|..||.:|::|||.:.|
Human   111 LLRLRLPVRVTSSVQPLPLPNDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATC--- 172

  Fly   184 TYG-YGSQIRNTMICA-AASGKDACQGDSGGPLVSGGVLVGVVSWGY--GCAYSNYPGVY 239
             :| |..:|.:.|:|| ...|:||||||||||||.||||.|:||||.  .|.....||||
Human   173 -HGVYPGRITSNMVCAGGVPGQDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVY 231

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alphaTry	NP_476771.1	Tryp_SPc	30..249	CDD:214473	81/227 (36%)
KLK12	NP_062544.1	Tryp_SPc	21..236	CDD:214473	81/227 (36%)
		Tryp_SPc	22..236	CDD:238113	81/226 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D469244at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X21
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.920