Protein Alignment alphaTry and KLK14

DIOPT Version :10

• Sequence 1: NP_476771.1
• Gene: alphaTry / 48316
• FlyBaseID: FBgn0003863
• Length: 256
• Species: Drosophila melanogaster
• Sequence 2: NP_071329.3
• Gene: KLK14 / 43847
• HGNCID: 6362
• Length: 251
• Species: Homo sapiens
• Alignment Length: 256
• Identity: 94/256 - (36%)
• Similarity: 131/256 - (51%)
• Gaps: 20/256 - (7%)

  Fly     6 ILLSAV-VCALGGTVPEGLLPQLDGRIVGGSATTISSFPWQISLQRSGSHS--CGGSIYSANIIV 67
            :||:|: |.|:..|..:    :.:.:|:||...|.||.|||.:|.......  |||::.|...::
Human     3 LLLTALQVLAIAMTQSQ----EDENKIIGGHTCTRSSQPWQAALLAGPRRRFLCGGALLSGQWVI 63

  Fly    68 TAAHCLQSVSASVLQVRAGS---TYWSSGGVVAKVSSFKNHEGYNANTMVNDIAVIRLSSSLSFS 129
            |||||    ...:|||..|.   ..|.:...|.:|.....|..||:.|..||:.:::|.......
Human    64 TAAHC----GRPILQVALGKHNLRRWEATQQVLRVVRQVTHPNYNSRTHDNDLMLLQLQQPARIG 124

  Fly   130 SSIKAISLATYNPANGASAAVSGWGTQSSGSSSIPSQLQYVNVNIVSQSQCASSTYGYGSQIRNT 194
            .:::.|.:.....:.|.|..||||||.||..:..|:.||.||:||.....|..:   |...|...
Human   125 RAVRPIEVTQACASPGTSCRVSGWGTISSPIARYPASLQCVNINISPDEVCQKA---YPRTITPG 186

  Fly   195 MICAAA--SGKDACQGDSGGPLVSGGVLVGVVSWGY-GCAYSNYPGVYADVAVLRSWVVST 252
            |:||..  .|||:||||||||||..|.|.|:||||. .||...|||||.::...|||:..|
Human   187 MVCAGVPQGGKDSCQGDSGGPLVCRGQLQGLVSWGMERCALPGYPGVYTNLCKYRSWIEET 247

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alphaTry	NP_476771.1	Tryp_SPc	30..249	CDD:214473	86/226 (38%)
KLK14	NP_071329.3	Tryp_SPc	25..247	CDD:238113	87/228 (38%)