DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment alphaTry and Tmprss9

DIOPT Version :9

Sequence 1:	NP_476771.1	Gene:	alphaTry / 48316	FlyBaseID:	FBgn0003863	Length:	256	Species:	Drosophila melanogaster
Sequence 2:	XP_006513905.2	Gene:	Tmprss9 / 432478	MGIID:	3612246	Length:	1342	Species:	Mus musculus

Alignment Length:	240	Identity:	91/240 - (37%)
Similarity:	124/240 - (51%)	Gaps:	16/240 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 GRIVGGSATTISSFPWQISLQRSGSHSCGGSIYSANIIVTAAHCLQSV-SASVLQVRAGSTYWS- 91
            ||||||.......||||:||:.:..|.||.:|..|..:|:||||.... ..:....:|||.:.|
Mouse   454 GRIVGGVEAAPGEFPWQVSLRENHEHFCGATIIGARWLVSAAHCFNEFQDPAQWAAQAGSVHLSG 518

  Fly    92 --SGGVVAKVSSFKNHEGYNANTMVNDIAVIRLSSSLSFSSSIKAISL--ATYNPANGASAAVSG 152
              :..|..:|.....|..|:|:|...|:||:.|:..|.|...::...|  ||:....|....:||
Mouse   519 SEASAVRTRVLRIAKHPAYDADTADFDVAVLELARPLPFGRYVQPACLPAATHVFPPGKKCLISG 583

  Fly   153 WGTQSSGSSSIPSQLQYVNVNIVSQSQCASSTYGYGSQIRNTMICAA-ASGK-DACQGDSGGPLV 215
            ||.........|..||...|.::.||.|:|.   ||..:.:.|:||. ..|| |:||||||||||
Mouse   584 WGYLKEDFLVKPEVLQKATVELLDQSLCSSL---YGHSLTDRMVCAGYLDGKVDSCQGDSGGPLV 645

  Fly   216 ----SGG-VLVGVVSWGYGCAYSNYPGVYADVAVLRSWVVSTANS 255
                ||. .|.|:||||.|||.:..||||..|..||.|::...::
Mouse   646 CEEPSGRFFLAGIVSWGIGCAEARRPGVYTRVTRLRDWILEVTSA 690

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
alphaTry	NP_476771.1	Tryp_SPc	30..249	CDD:214473	89/231 (39%)
Tmprss9	XP_006513905.2	SEA	285..365	CDD:366610
		LDLa	407..442	CDD:238060
		Tryp_SPc	455..684	CDD:214473	89/231 (39%)
		Tryp_SPc	756..984	CDD:214473
		Tryp_SPc	1085..1336	CDD:238113
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910