DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment alphaTry and MP1

DIOPT Version :9

Sequence 1:	NP_476771.1	Gene:	alphaTry / 48316	FlyBaseID:	FBgn0003863	Length:	256	Species:	Drosophila melanogaster
Sequence 2:	NP_001303421.1	Gene:	MP1 / 40541	FlyBaseID:	FBgn0027930	Length:	400	Species:	Drosophila melanogaster

Alignment Length:	266	Identity:	80/266 - (30%)
Similarity:	123/266 - (46%)	Gaps:	54/266 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 RIVGGSATTISSFPWQ--ISLQRSGS---HSCGGSIYSANIIVTAAHCLQSVSA--SVLQVRAGS 87
            |:|||:.||...|||.  |...:.|:   |.||||:.:...::|||||:.::.:  .:..||.|.
  Fly   137 RVVGGNETTKREFPWMALIEYTKPGNVKGHHCGGSLINHRYVLTAAHCVSAIPSDWELTGVRLGE 201

  Fly    88 TYWSSGG----VVAKVSSFKNHEGY----------------NANTMVNDIAVIRLSSSLSFSSSI 132
              |.:..    .|.|......:|.|                |:...:||||::||...:.:|..|
  Fly   202 --WDASTNPDCTVGKNGRRDCNEPYVDYPVEERIPHPQYPGNSRDQLNDIALLRLRDEVQYSDFI 264

  Fly   133 KAISLATY-----NPANGASAAVSGWG-TQSSGSSSIPSQLQYVNVNIVSQSQCASSTYGYGSQI 191
            ..:.|.|.     |...|....|:||| |:::.:|:|..:.:   ::.|..|:|   ...|.:|.
  Fly   265 LPVCLPTLASQHNNIFLGRKVVVAGWGRTETNFTSNIKLKAE---LDTVPTSEC---NQRYATQR 323

  Fly   192 RNT---MICA-AASGKDACQGDSGGPLV--------SGGVLVGVVSWG-YGCAYSNYPGVYADVA 243
            |..   .:|| ...|.|:|:|||||||:        |...:.||||:| ..|....:||||..|.
  Fly   324 RTVTTKQMCAGGVEGVDSCRGDSGGPLLLEDYSNGNSNYYIAGVVSYGPTPCGLKGWPGVYTRVE 388

  Fly   244 VLRSWV 249
            ...:|:
  Fly   389 AYLNWI 394

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
alphaTry	NP_476771.1	Tryp_SPc	30..249	CDD:214473	79/264 (30%)
MP1	NP_001303421.1	CLIP	29..91	CDD:288855
		Tryp_SPc	137..394	CDD:214473	79/264 (30%)
		Tryp_SPc	138..397	CDD:238113	79/265 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910