DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment alphaTry and TMPRSS7

DIOPT Version :9

Sequence 1:	NP_476771.1	Gene:	alphaTry / 48316	FlyBaseID:	FBgn0003863	Length:	256	Species:	Drosophila melanogaster
Sequence 2:	NP_001382436.1	Gene:	TMPRSS7 / 344805	HGNCID:	30846	Length:	843	Species:	Homo sapiens

Alignment Length:	243	Identity:	84/243 - (34%)
Similarity:	121/243 - (49%)	Gaps:	35/243 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 RIVGGSATTISSFPWQISLQRSGSHSCGGSIYSANIIVTAAHCLQSVSASVLQVRAGSTYWS--- 91
            ||:||:.|....:|||:||...||..||.|:.|...:::||||......|      ..|.|:
Human   605 RIIGGTDTLEGGWPWQVSLHFVGSAYCGASVISREWLLSAAHCFHGNRLS------DPTPWTAHL 663

  Fly    92 ------SGGVVAKVSSFKNHEGYNANTMVNDIAVIRLSSSLSFSSSIKAISLATYNP------AN 144
                  :...|:.|.....||.||:.|...|||:::|  |:::..::|.:......|      .:
Human   664 GMYVQGNAKFVSPVRRIVVHEYYNSQTFDYDIALLQL--SIAWPETLKQLIQPICIPPTGQRVRS 726

  Fly   145 GASAAVSGWGTQSSGSSSIPSQLQYVNVNIVSQSQCASSTYGYGSQIRNTMICAA-ASGK-DACQ 207
            |....|:|||.:....:.....||...|.::.|:.|. ||||.   |.:.|:||. .||| |||:
Human   727 GEKCWVTGWGRRHEADNKGSLVLQQAEVELIDQTLCV-STYGI---ITSRMLCAGIMSGKRDACK 787

  Fly   208 GDSGGPL----VSGG--VLVGVVSWGYGCAYSNYPGVYADVAVLRSWV 249
            |||||||    .|.|  :|.|:||||:|....|:||||..|:....|:
Human   788 GDSGGPLSCRRKSDGKWILTGIVSWGHGSGRPNFPGVYTRVSNFVPWI 835

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
alphaTry	NP_476771.1	Tryp_SPc	30..249	CDD:214473	83/241 (34%)
TMPRSS7	NP_001382436.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	27..67
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910