DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment alphaTry and tmprss4b

DIOPT Version :9

Sequence 1:	NP_476771.1	Gene:	alphaTry / 48316	FlyBaseID:	FBgn0003863	Length:	256	Species:	Drosophila melanogaster
Sequence 2:	NP_001119849.1	Gene:	tmprss4b / 327651	ZFINID:	ZDB-GENE-030131-5862	Length:	432	Species:	Danio rerio

Alignment Length:	239	Identity:	92/239 - (38%)
Similarity:	125/239 - (52%)	Gaps:	30/239 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 DGRIVGGSATTISSFPWQISLQRSGSHSCGGSIYSANIIVTAAHCL----QSVS--------ASV 80
            :.|||||..|:|..:|||:|||.:..|.||||:.|.:.|::||||.    |.:|        ..|
Zfish   199 EDRIVGGVETSIEHWPWQVSLQFNHRHMCGGSLLSTSWIISAAHCFTGRTQELSRWTVVLGQTKV 263

  Fly    81 LQVRAGSTYWSSGGVVAKVSSFKNHEGYNANTMVNDIAVIRLSSSLSFSSSIKAISLATYNPANG 145
            :.|           |...|.....|:.||..|...|||:::|:..:....||..:.|..:..|..
Zfish   264 MDV-----------VGVSVDMIVIHKDYNRLTNDFDIAMLKLTWPVKTGESILPVCLPPHQLAIK 317

  Fly   146 ASAAVSGWGTQSSGSSSIPSQLQYVNVNIVSQSQCASSTYGYGSQIRNTMICAA--ASGKDACQG 208
            ....|:|||....| .::|:.||..:|.:|::|:|:..|. |.|.|...|:||.  ....|||||
Zfish   318 DMLVVTGWGLLKEG-GALPTVLQKASVPLVNRSECSKPTI-YSSSITPRMLCAGFLQGNVDACQG 380

  Fly   209 DSGGPLV---SGGVLVGVVSWGYGCAYSNYPGVYADVAVLRSWV 249
            |||||||   |...|:|:||||.|||....|||||||..|..|:
Zfish   381 DSGGPLVYLSSRWQLIGIVSWGVGCAREGKPGVYADVTQLLDWI 424

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
alphaTry	NP_476771.1	Tryp_SPc	30..249	CDD:214473	91/235 (39%)
tmprss4b	NP_001119849.1	SRCR_2	100..179	CDD:292133
		SRCR	105..>175	CDD:278931
		Tryp_SPc	201..424	CDD:214473	91/235 (39%)
		Tryp_SPc	202..427	CDD:238113	91/236 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910