DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment alphaTry and plg

DIOPT Version :9

Sequence 1:	NP_476771.1	Gene:	alphaTry / 48316	FlyBaseID:	FBgn0003863	Length:	256	Species:	Drosophila melanogaster
Sequence 2:	NP_958880.2	Gene:	plg / 322691	ZFINID:	ZDB-GENE-030131-1411	Length:	818	Species:	Danio rerio

Alignment Length:	254	Identity:	79/254 - (31%)
Similarity:	124/254 - (48%)	Gaps:	34/254 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 CALGGTVPEGLLPQLDGRIVGGSATTISSFPWQISLQRSGS-HSCGGSIYSANIIVTAAHCLQ-S 75
            |....|.|:    :..||||||..:...|:||||||:..|. |.|||::.....:|||||||: |
Zfish   575 CGQPATKPK----RCFGRIVGGCVSKPHSWPWQISLRTRGKIHFCGGTLIDPQWVVTAAHCLERS 635

  Fly    76 VSASVLQVRAGSTYWSSGGVVAKVSSFKNHEGYNANTMV-----NDIAVIRLSSSLSFSSSIKAI 135
            .|.|..::..        |:..:.::..:.:..:...::     .|||:::|......:..:..:
Zfish   636 DSPSAYKIML--------GIHTERATESSKQERDVTKIIKGPAGTDIALLKLDRPALINDKVSPV 692

  Fly   136 SLATYN---PANGASAAVSGWG-TQSSGSSSIPSQLQYVNVNIVSQSQCASSTYGYGSQIRNTMI 196
            .|...:   |:| ....|:||| ||.:|..   ..|:.....::....|...::..| ::::..:
Zfish   693 CLPEKDYIVPSN-TECYVTGWGETQDTGGE---GYLKETGFPVIENKVCNRPSFLNG-RVKDHEM 752

  Fly   197 CAA--ASGKDACQGDSGGPLV----SGGVLVGVVSWGYGCAYSNYPGVYADVAVLRSWV 249
            ||.  ..|.|:||||||||||    :..||.||.|||.|||.:..||||..|:....|:
Zfish   753 CAGNIEGGNDSCQGDSGGPLVCYAQNTFVLQGVTSWGLGCANAMKPGVYTRVSKFVDWI 811

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
alphaTry	NP_476771.1	Tryp_SPc	30..249	CDD:214473	74/235 (31%)
plg	NP_958880.2	PAN_AP_HGF	31..104	CDD:238532
		KR	109..190	CDD:214527
		KR	190..270	CDD:214527
		KR	281..361	CDD:214527
		Kringle	376..453	CDD:306546
		KR	490..572	CDD:214527
		Tryp_SPc	589..813	CDD:238113	74/236 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910