DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment alphaTry and Tmprss11e

DIOPT Version :9

Sequence 1:	NP_476771.1	Gene:	alphaTry / 48316	FlyBaseID:	FBgn0003863	Length:	256	Species:	Drosophila melanogaster
Sequence 2:	XP_038948843.1	Gene:	Tmprss11e / 305265	RGDID:	1561698	Length:	444	Species:	Rattus norvegicus

Alignment Length:	243	Identity:	82/243 - (33%)
Similarity:	118/243 - (48%)	Gaps:	27/243 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 QLDGRIVGGSATTISSFPWQISLQRSGSHSCGGSIYSANIIVTAAHCLQSVSASVLQVRAGSTYW 90
            |...|||||::.....:|||.|||..|||.||.::.|...:|:||||.::       .:..|.:.
  Rat   208 QTSVRIVGGTSAEEGEWPWQSSLQWDGSHRCGATLISNTWLVSAAHCFRT-------HKDPSRWT 265

  Fly    91 SSGGVVAKVSSFKN-------HEGYNANTMVNDIAVIRLSSSLSFSSSIKAISL--ATYNPANGA 146
            :|.|...:......       ||.||..:...|||::.||..:..::::..:.|  |.:....|.
  Rat   266 ASFGATLQPPKLTTGIRRIIVHEKYNYPSHDYDIALVELSRPVPCTNAVHKVCLPDANHEFQPGQ 330

  Fly   147 SAAVSGWGT-QSSGSSSIPSQLQYVNVNIVSQSQCASSTYGYGSQIRNTMICAA--ASGKDACQG 208
            ...|:|:|. ::.|.:.  :.|:.|.|:.:....| :....|...|...|:||.  ...||||||
  Rat   331 RMFVTGFGALRNDGFAQ--NYLRQVQVDYIDTQTC-NRPQSYNGAITPRMLCAGFLKGEKDACQG 392

  Fly   209 DSGGPLVSGGV-----LVGVVSWGYGCAYSNYPGVYADVAVLRSWVVS 251
            |||||||:..|     |.||||||..|...|.||||..|...|.|:.|
  Rat   393 DSGGPLVTPDVRDVWYLAGVVSWGDECGQPNKPGVYTRVTAFRDWITS 440

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
alphaTry	NP_476771.1	Tryp_SPc	30..249	CDD:214473	79/235 (34%)
Tmprss11e	XP_038948843.1	SEA	71..176	CDD:396113
Tmprss11e	XP_038948843.1	Tryp_SPc	213..441	CDD:238113	80/238 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X21
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000