Protein Alignment alphaTry and GZMA

DIOPT Version :10

• Sequence 1: NP_476771.1
• Gene: alphaTry / 48316
• FlyBaseID: FBgn0003863
• Length: 256
• Species: Drosophila melanogaster
• Sequence 2: NP_006135.2
• Gene: GZMA / 3001
• HGNCID: 4708
• Length: 262
• Species: Homo sapiens
• Alignment Length: 259
• Identity: 71/259 - (27%)
• Similarity: 116/259 - (44%)
• Gaps: 27/259 - (10%)

  Fly     8 LSAVVCALGGTVPEGLLPQLDGRIVGGSATTISSFPWQISLQRSGSHSCGGSIYSANIIVTAAHC 72
            ||.||..|  .:||.:..    :|:||:..|..|.|:.:.|.......|.|::.:.:.::|||||
Human    12 LSVVVSLL--LIPEDVCE----KIIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHC 70

  Fly    73 LQSVSASVLQVRAGSTYWSSGGVVAKVSSFKNHEGYNANTMVNDIAVIRLSSSLSFSSSIKAISL 137
            ..:..:.|:......|.......:..|.....:..|:..|...|:.:::|......:..:..:.|
Human    71 NLNKRSQVILGAHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHL 135

  Fly   138 A----TYNPANGASAAVSGWGTQSSGSSSIPSQLQYVNVNIVSQSQCAS-STYGYGSQIRNTMIC 197
            .    ...|  |....|:||| ::..|:|....|:.||:.|:.:..|.. :.|.:...|...|:|
Human   136 PKKGDDVKP--GTMCQVAGWG-RTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVC 197

  Fly   198 AAA--SGKDACQGDSGGPLVSGGVLVGVVSWGY--GCAYSNYPGVYADVAVLRS-----WVVST 252
            |.:  .|:|:|.||||.||:..||..||.|:|.  .|.....||||    :|.|     |::.|
Human   198 AGSLRGGRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVY----ILLSKKHLNWIIMT 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alphaTry	NP_476771.1	Tryp_SPc	30..249	CDD:214473	62/232 (27%)
GZMA	NP_006135.2	Tryp_SPc	29..254	CDD:238113	62/231 (27%)