DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment alphaTry and Klk10

DIOPT Version :9

Sequence 1:	NP_476771.1	Gene:	alphaTry / 48316	FlyBaseID:	FBgn0003863	Length:	256	Species:	Drosophila melanogaster
Sequence 2:	NP_001004100.1	Gene:	Klk10 / 292850	RGDID:	1303242	Length:	279	Species:	Rattus norvegicus

Alignment Length:	256	Identity:	74/256 - (28%)
Similarity:	113/256 - (44%)	Gaps:	44/256 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 GGTVPEGLLPQLDGRIVGGSATTISSFPWQISLQRSGSHSCGGSIYSANIIVTAAHCLQSVSASV 80
            |.|..|.|      ...|....::|. |||:||..:....|.|.:...|.::|||||.::   ..
  Rat    39 GNTTREDL------EAFGTLCPSVSQ-PWQVSLFHNLQFQCAGVLVDQNWVLTAAHCWRN---KP 93

  Fly    81 LQVRAGSTYWSSGGVVAKVSSFKNHEGYNANTMV-------------------NDIAVIRLSSSL 126
            |:.|.|..:         :..|::.:..:.|:.|                   :|:.:::|||.:
  Rat    94 LRARVGDDH---------LLLFQSEQLRSTNSPVFHPKYQPCSGPVLPLRSDEHDLMMLKLSSPV 149

  Fly   127 SFSSSIKAISLATYNPANGASAAVSGWGTQSSGSSSIPSQLQYVNVNIVSQSQCASSTYGYGSQI 191
            ..:|.:..:.|............||||||.::........|....|.::||.||  .|: |...|
  Rat   150 VLTSKVHPVQLPFQCAQPRQECQVSGWGTTANRRVKYNRSLSCSRVTLLSQKQC--ETF-YPGVI 211

  Fly   192 RNTMICAAAS-GKDACQGDSGGPLVSGGVLVGVVSWG-YGC-AYSNYPGVYADVAVLRSWV 249
            .|.||||... .:|:||.|||||||....|.|::||. |.| |.:.||.|||.:....:|:
  Rat   212 TNNMICAGMDRDQDSCQSDSGGPLVCDNTLHGILSWSIYPCGAATQYPAVYAKICNYTNWI 272

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
alphaTry	NP_476771.1	Tryp_SPc	30..249	CDD:214473	69/240 (29%)
Klk10	NP_001004100.1	Tryp_SPc	50..272	CDD:214473	69/237 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	148	1.000	Domainoid score	I4330
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D469244at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X21
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.920