DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment alphaTry and Tmprss11g

DIOPT Version :9

Sequence 1:	NP_476771.1	Gene:	alphaTry / 48316	FlyBaseID:	FBgn0003863	Length:	256	Species:	Drosophila melanogaster
Sequence 2:	NP_001008554.1	Gene:	Tmprss11g / 289546	RGDID:	1306446	Length:	417	Species:	Rattus norvegicus

Alignment Length:	252	Identity:	93/252 - (36%)
Similarity:	130/252 - (51%)	Gaps:	19/252 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 CALGGTVPEGLLPQLDGRIVGGSATTISSFPWQISLQRSGSHSCGGSIYSANIIVTAAHCLQSV- 76
            |.||...|.      ..||..|.....:|:|||.|||..|.|.||.|:..:..:||:|||..:.
  Rat   174 CGLGMEYPR------IARIADGKPAGSNSWPWQSSLQVEGIHLCGASLIGSQWLVTSAHCFDNYK 232

  Fly    77 SASVLQVRAGSTYWSSGGVVAKVSSFKNHEGYNANTMVNDIAVIRLSSSLSFSSSIKAISL--AT 139
            :..:..|..|.|. .:.....||.|...||.|.|:...:||||::|||.:.||.:::.:.|  ||
  Rat   233 NPKLWTVSFGRTL-GNPLTTRKVESIIIHENYAAHKHDDDIAVVKLSSPVLFSENLRTVCLPEAT 296

  Fly   140 YNPANGASAAVSGWGTQSSGSSSIPSQLQYVNVNIVSQSQCASSTYGYGSQIRNTMICAA-ASGK 203
            :.....:...|:|||...: :...|:.||.|.:.|:|...| :....||..|.:.||||. .:||
  Rat   297 FQVLPKSKVFVTGWGALKA-NGPFPNSLQEVEIEIISNDVC-NQVNVYGGAISSGMICAGFLTGK 359

  Fly   204 -DACQGDSGGPLV-----SGGVLVGVVSWGYGCAYSNYPGVYADVAVLRSWVVSTAN 254
             |||:||||||||     :...|:|:||||..|...|.||:|..|...|:|:.|..|
  Rat   360 LDACEGDSGGPLVISDNRNKWYLLGIVSWGIDCGKENKPGIYTRVTHYRNWIKSKTN 416

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
alphaTry	NP_476771.1	Tryp_SPc	30..249	CDD:214473	86/228 (38%)
Tmprss11g	NP_001008554.1	SEA	48..142	CDD:279699
		Tryp_SPc	185..411	CDD:214473	86/228 (38%)
		Tryp_SPc	186..414	CDD:238113	86/230 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X21
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910