DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment alphaTry and Klk8

DIOPT Version :9

Sequence 1:	NP_476771.1	Gene:	alphaTry / 48316	FlyBaseID:	FBgn0003863	Length:	256	Species:	Drosophila melanogaster
Sequence 2:	NP_001311327.1	Gene:	Klk8 / 259277	MGIID:	1343327	Length:	260	Species:	Mus musculus

Alignment Length:	242	Identity:	80/242 - (33%)
Similarity:	113/242 - (46%)	Gaps:	15/242 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 GLLPQLDGRIVGGSATTISSFPWQISLQRSGSHSCGGSIYSANIIVTAAHCLQSVSASVLQVRAG 86
            ||......:|:.|......|.|||.:|.:.....|||.:.....::|||||    ......||.|
Mouse    24 GLTRAQGSKILEGRECIPHSQPWQAALFQGERLICGGVLVGDRWVLTAAHC----KKQKYSVRLG 84

  Fly    87 STYWSSGG---VVAKVSSFKNHEGYNANT---MVNDIAVIRLSSSLSFSSSIKAISLATYNPANG 145
            .....|..   ...:|:....|..||.:.   ..:||.:|||.:|.:....:|.:.||...|..|
Mouse    85 DHSLQSRDQPEQEIQVAQSIQHPCYNNSNPEDHSHDIMLIRLQNSANLGDKVKPVQLANLCPKVG 149

  Fly   146 ASAAVSGWGTQSSGSSSIPSQLQYVNVNIVSQSQCASSTYGYGSQIRNTMICAAAS-GKDACQGD 209
            ....:|||||.:|...:.|:.|....|.|.||::|..:   |..:|...|:||.:| |.|.||||
Mouse   150 QKCIISGWGTVTSPQENFPNTLNCAEVKIYSQNKCERA---YPGKITEGMVCAGSSNGADTCQGD 211

  Fly   210 SGGPLVSGGVLVGVVSWGYG-CAYSNYPGVYADVAVLRSWVVSTANS 255
            ||||||..|:|.|:.|||.. |.....||||..:....:|:..|.::
Mouse   212 SGGPLVCDGMLQGITSWGSDPCGKPEKPGVYTKICRYTTWIKKTMDN 258

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
alphaTry	NP_476771.1	Tryp_SPc	30..249	CDD:214473	76/226 (34%)
Klk8	NP_001311327.1	Tryp_SPc	32..252	CDD:214473	76/226 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	156	1.000	Domainoid score	I4174
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X21
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910