DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment alphaTry and Klkb1

DIOPT Version :9

Sequence 1:	NP_476771.1	Gene:	alphaTry / 48316	FlyBaseID:	FBgn0003863	Length:	256	Species:	Drosophila melanogaster
Sequence 2:	NP_036857.2	Gene:	Klkb1 / 25048	RGDID:	67382	Length:	638	Species:	Rattus norvegicus

Alignment Length:	257	Identity:	89/257 - (34%)
Similarity:	123/257 - (47%)	Gaps:	42/257 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 QLDGRIVGGSATTISSFPWQISLQ---RSGSHSCGGSIYSANIIVTAAHCLQSVSASVLQVRAGS 87
            :::.|||||:.:::..:|||:|||   .|.:|.|||||.....|:|||||..           |.
  Rat   386 KINARIVGGTNSSLGEWPWQVSLQVKLVSQNHMCGGSIIGRQWILTAAHCFD-----------GI 439

  Fly    88 TY---WSSGGVVAKVSSFKN------------HEGYNANTMVNDIAVIRLSSSLSFSSSIKAISL 137
            .|   |...|.:..:|...|            |:.|..:....|||:|:|.:.|:::...|.|.|
  Rat   440 PYPDVWRIYGGILNLSEITNKTPFSSIKELIIHQKYKMSEGSYDIALIKLQTPLNYTEFQKPICL 504

  Fly   138 ATYNPANG--ASAAVSGWG-TQSSGSSSIPSQLQYVNVNIVSQSQCASSTYGYGSQIRNTMICAA 199
            .:....|.  .:..|:||| |:..|.:.  :.||...:.:|...:|......|  .|...||||.
  Rat   505 PSKADTNTIYTNCWVTGWGYTKERGETQ--NILQKATIPLVPNEECQKKYRDY--VITKQMICAG 565

  Fly   200 --ASGKDACQGDSGGPLV---SG-GVLVGVVSWGYGCAYSNYPGVYADVAVLRSWVVSTANS 255
              ..|.|||:||||||||   || ..|||:.|||.|||....||||..||....|::....|
  Rat   566 YKEGGIDACKGDSGGPLVCKHSGRWQLVGITSWGEGCARKEQPGVYTKVAEYIDWILEKIQS 627

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
alphaTry	NP_476771.1	Tryp_SPc	30..249	CDD:214473	87/245 (36%)
Klkb1	NP_036857.2	APPLE	21..104	CDD:128519
		APPLE	111..194	CDD:128519
		APPLE	201..284	CDD:128519
		APPLE	292..375	CDD:128519
		Tryp_SPc	390..621	CDD:214473	87/245 (36%)
		Tryp_SPc	391..621	CDD:238113	86/244 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910