DRSC/TRiP Functional Genomics Resources

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Protein Alignment alphaTry and Klk7

DIOPT Version :9

Sequence 1:NP_476771.1 Gene:alphaTry / 48316 FlyBaseID:FBgn0003863 Length:256 Species:Drosophila melanogaster
Sequence 2:NP_036002.1 Gene:Klk7 / 23993 MGIID:1346336 Length:249 Species:Mus musculus


Alignment Length:254 Identity:90/254 - (35%)
Similarity:123/254 - (48%) Gaps:23/254 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly     4 IVILLSAVVCALGGTVPEGLLPQLDGRIVGGSATTISSFPWQISLQRSGSHSCGGSIYSANIIVT 68
            |.:|||..:    .|..:|      .||:.|......|.|||::|.:.....|||.:.....::|
Mouse     9 ITVLLSLAL----ETAGQG------ERIIDGYKCKEGSHPWQVALLKGNQLHCGGVLVDKYWVLT 63

  Fly    69 AAHCLQSVSASVLQVRAGSTYW--SSGGVVAKVSSFKNHEGYNANTMVNDIAVIRLSSSLSFSSS 131
            ||||    .....||:.||...  .|...:....||: |.||:..|.||||.::||...:..||.
Mouse    64 AAHC----KMGQYQVQLGSDKIGDQSAQKIKATKSFR-HPGYSTKTHVNDIMLVRLDEPVKMSSK 123

  Fly   132 IKAISLATYNPANGASAAVSGWGTQSSGSSSIPSQLQYVNVNIVSQSQCASSTYGYGSQIRNTMI 196
            ::|:.|..:....|.|..||||||.:|...:.||.|...:|.::|..:|...   |...:..||:
Mouse   124 VEAVQLPEHCEPPGTSCTVSGWGTTTSPDVTFPSDLMCSDVKLISSRECKKV---YKDLLGKTML 185

  Fly   197 CAAA--SGKDACQGDSGGPLVSGGVLVGVVSWG-YGCAYSNYPGVYADVAVLRSWVVST 252
            ||..  |..:.|.||||||||....|.|:|||| |.|...|.||||..|...:.||:.|
Mouse   186 CAGIPDSKTNTCNGDSGGPLVCNDTLQGLVSWGTYPCGQPNDPGVYTQVCKYKRWVMET 244

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
alphaTryNP_476771.1 Tryp_SPc 30..249 CDD:214473 81/223 (36%)
Klk7NP_036002.1 Tryp_SPc 25..241 CDD:214473 81/223 (36%)
Serine protease. /evidence=ECO:0000250 26..246 83/227 (37%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 156 1.000 Domainoid score I4174
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X21
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
43.910

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