DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment alphaTry and Habp2

DIOPT Version :9

Sequence 1:	NP_476771.1	Gene:	alphaTry / 48316	FlyBaseID:	FBgn0003863	Length:	256	Species:	Drosophila melanogaster
Sequence 2:	NP_001316864.1	Gene:	Habp2 / 226243	MGIID:	1196378	Length:	554	Species:	Mus musculus

Alignment Length:	248	Identity:	81/248 - (32%)
Similarity:	113/248 - (45%)	Gaps:	32/248 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 RIVGGSATTISSFPWQISLQRS--------GSHSCGGSIYSANIIVTAAHCLQSVSASVLQVRAG 86
            ||.||..:|....|||:|||.|        ..|.|||::.....::||||| ..::...|:|..|
Mouse   307 RIYGGFKSTAGKHPWQVSLQTSLPLTTSMPQGHFCGGALIHPCWVLTAAHC-TDINTKHLKVVLG 370

  Fly    87 S---TYWSSGGVVAKVSSFKNHEGYNANTMV--NDIAVIRLS-----SSLSFSSSIKAISLATYN 141
            .   ....|.....:|.....:..||....:  ||||:::|.     .:|. |..:|.:.|.:..
Mouse   371 DQDLKKTESHEQTFRVEKILKYSQYNERDEIPHNDIALLKLKPVGGHCALE-SRYVKTVCLPSDP 434

  Fly   142 PANGASAAVSGWGTQSSGSSSIPSQLQYVNVNIVSQSQCASSTYGYGSQIRNTMICAA---ASGK 203
            ..:|....:||||...:|..|  .||....|.:::...| :|...|...|.::||||.   ..|.
Mouse   435 FPSGTECHISGWGVTETGEGS--RQLLDAKVKLIANPLC-NSRQLYDHTIDDSMICAGNLQKPGS 496

  Fly   204 DACQGDSGGPLV---SGGVLV-GVVSWGYGCAYSNYPGVYADVAVLRSWVVST 252
            |.|||||||||.   .|...| |:||||..|  ...||||..|....:|:.:|
Mouse   497 DTCQGDSGGPLTCEKDGTYYVYGIVSWGQEC--GKKPGVYTQVTKFLNWIKTT 547

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
alphaTry	NP_476771.1	Tryp_SPc	30..249	CDD:214473	79/243 (33%)
Habp2	NP_001316864.1	EGF_CA	67..103	CDD:238011
		EGF_CA	150..182	CDD:238011
		KR	187..271	CDD:238056
		Tryp_SPc	308..547	CDD:238113	79/245 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000