DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment alphaTry and Try4

DIOPT Version :9

Sequence 1:	NP_476771.1	Gene:	alphaTry / 48316	FlyBaseID:	FBgn0003863	Length:	256	Species:	Drosophila melanogaster
Sequence 2:	NP_035776.1	Gene:	Try4 / 22074	MGIID:	102757	Length:	246	Species:	Mus musculus

Alignment Length:	259	Identity:	92/259 - (35%)
Similarity:	140/259 - (54%)	Gaps:	25/259 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LKIVILLSAVVCALGGTVPEGLLPQLDGRIVGGSATTISSFPWQISLQRSGSHSCGGSIYSANII 66
            ::.::.|:.|..|:...|.:      |.:||||.....:|.|:|:|| .||.|.||||:.:...:
Mouse     1 MRALLFLALVGAAVAFPVDD------DDKIVGGYTCRENSVPYQVSL-NSGYHFCGGSLINDQWV 58

  Fly    67 VTAAHCLQSVSASVLQVRAGSTYWSSGGVVAKVSSFKN------HEGYNANTMVNDIAVIRLSSS 125
            |:||||.:    |.:|||.|.   .:..|:.....|.|      |..:|:.|:.|||.:|:|:|.
Mouse    59 VSAAHCYK----SRIQVRLGE---HNINVLEGNEQFVNSAKIIKHPNFNSRTLNNDIMLIKLASP 116

  Fly   126 LSFSSSIKAISLATYNPANGASAAVSGWGTQSSGSSSIPSQLQYVNVNIVSQSQCASSTYGYGSQ 190
            ::.::.:..::|.:.....|....:||||...|...:.|..||.::..::.|:.|.:|   |..:
Mouse   117 VTLNARVATVALPSSCAPAGTQCLISGWGNTLSFGVNNPDLLQCLDAPLLPQADCEAS---YPGK 178

  Fly   191 IRNTMICAA--ASGKDACQGDSGGPLVSGGVLVGVVSWGYGCAYSNYPGVYADVAVLRSWVVST 252
            |.|.|||..  ..|||:||||||||:|..|.|.|:||||||||..:.||||..|.....|:.:|
Mouse   179 ITNNMICVGFLEGGKDSCQGDSGGPVVCNGQLQGIVSWGYGCALKDNPGVYTKVCNYVDWIQNT 242

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
alphaTry	NP_476771.1	Tryp_SPc	30..249	CDD:214473	85/226 (38%)
Try4	NP_035776.1	Tryp_SPc	23..239	CDD:214473	85/226 (38%)
Try4	NP_035776.1	Tryp_SPc	24..242	CDD:238113	86/228 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BBP0
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D469244at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X21
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.820