Protein Alignment alphaTry and CFD

DIOPT Version :10

• Sequence 1: NP_476771.1
• Gene: alphaTry / 48316
• FlyBaseID: FBgn0003863
• Length: 256
• Species: Drosophila melanogaster
• Sequence 2: NP_001304264.1
• Gene: CFD / 1675
• HGNCID: 2771
• Length: 260
• Species: Homo sapiens
• Alignment Length: 263
• Identity: 79/263 - (30%)
• Similarity: 133/263 - (50%)
• Gaps: 25/263 - (9%)

  Fly     2 LKIVILLSAVVC---ALGGTVPEGLLPQLDGRIVGGSATTISSFPWQISLQRSGSHSCGGSIYSA 63
            |.:::||.|..|   |.....|    |:  |||:||......:.|:..|:|.:|:|.|||.:.:.
Human     7 LAVLVLLGAAACGEEAWAWAAP----PR--GRILGGREAEAHARPYMASVQLNGAHLCGGVLVAE 65

  Fly    64 NIIVTAAHCLQSVSASVLQVRAGSTYWSSG-------GVVAKVSSFKNHEGYNANTMVNDIAVIR 121
            ..:::|||||:..:...:||..|:...|..       .|:..|.    |.....:|:.:|:.:::
Human    66 QWVLSAAHCLEDAADGKVQVLLGAHSLSQPEPSKRLYDVLRAVP----HPDSQPDTIDHDLLLLQ 126

  Fly   122 LSSSLSFSSSIKAI--SLATYNPANGASAAVSGWGTQSSGSSSIPSQLQYVNVNIVSQSQCASST 184
            ||...:...:::.:  .....:.|.|....|:|||..:..... |..||:|.:.::.::.|...|
Human   127 LSEKATLGPAVRPLPWQRVDRDVAPGTLCDVAGWGIVNHAGRR-PDSLQHVLLPVLDRATCNRRT 190

  Fly   185 YGYGSQIRNTMICAAASGKDACQGDSGGPLVSGGVLVGVVSWGYG-CAYSNYPGVYADVAVLRSW 248
            :..|: |...::||.::.:|:|:||||||||.||||.|||:.|.. |.....||:|..||...:|
Human   191 HHDGA-ITERLMCAESNRRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTRVASYAAW 254

  Fly   249 VVS 251
            :.|
Human   255 IDS 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alphaTry	NP_476771.1	Tryp_SPc	30..249	CDD:214473	68/228 (30%)
CFD	NP_001304264.1	Tryp_SPc	33..258	CDD:238113	69/231 (30%)