Protein Alignment alphaTry and CTRB1

DIOPT Version :10

• Sequence 1: NP_476771.1
• Gene: alphaTry / 48316
• FlyBaseID: FBgn0003863
• Length: 256
• Species: Drosophila melanogaster
• Sequence 2: NP_001897.4
• Gene: CTRB1 / 1504
• HGNCID: 2521
• Length: 263
• Species: Homo sapiens
• Alignment Length: 273
• Identity: 103/273 - (37%)
• Similarity: 147/273 - (53%)
• Gaps: 33/273 - (12%)

  Fly     2 LKIVILLSAVVCALGGTVPEGLLPQLDG--RIVGGSATTISSFPWQISLQ-RSGSHSCGGSIYSA 63
            |.::...|.|..|.|..|| .:.|.|.|  |||.|......|:|||:||| ::|.|.||||:.|.
Human     4 LWLLSCFSLVGAAFGCGVP-AIHPVLSGLSRIVNGEDAVPGSWPWQVSLQDKTGFHFCGGSLISE 67

  Fly    64 NIIVTAAHCLQSVSASVLQVRAGSTYWSSGG--------VVAKVSSFKNHEGYNANTMVNDIAVI 120
            :.:||||||....|..|:   ||.  :..|.        .:|||  |||.: ::..|:.|||.::
Human    68 DWVVTAAHCGVRTSDVVV---AGE--FDQGSDEENIQVLKIAKV--FKNPK-FSILTVNNDITLL 124

  Fly   121 RLSSSLSFSSSIKAISLATYN---PANGASAAVSGWGTQSSGSSSIPSQLQYVNVNIVSQSQCAS 182
            :|::...||.::.|:.|.:.:   || |...|.:|||.....::..|.:||...:.::|.::|..
Human   125 KLATPARFSQTVSAVCLPSADDDFPA-GTLCATTGWGKTKYNANKTPDKLQQAALPLLSNAECKK 188

  Fly   183 STYGYGSQIRNTMICAAASGKDACQGDSGGPLV----SGGVLVGVVSWGYGCAYSNYPGVYADVA 243
            |   :|.:|.:.||||.|||..:|.||||||||    ....|||:||||.....::.|||||.|.
Human   189 S---WGRRITDVMICAGASGVSSCMGDSGGPLVCQKDGAWTLVGIVSWGSDTCSTSSPGVYARVT 250

  Fly   244 VLRSWV--VSTAN 254
            .|..||  :..||
Human   251 KLIPWVQKILAAN 263

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alphaTry	NP_476771.1	Tryp_SPc	30..249	CDD:214473	89/234 (38%)
CTRB1	NP_001897.4	Tryp_SPc	34..259	CDD:238113	90/236 (38%)