DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment alphaTry and CLIPB2

DIOPT Version :9

Sequence 1:	NP_476771.1	Gene:	alphaTry / 48316	FlyBaseID:	FBgn0003863	Length:	256	Species:	Drosophila melanogaster
Sequence 2:	XP_312956.3	Gene:	CLIPB2 / 1273920	VectorBaseID:	AGAP003246	Length:	355	Species:	Anopheles gambiae

Alignment Length:	268	Identity:	92/268 - (34%)
Similarity:	132/268 - (49%)	Gaps:	40/268 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 TVPE-GLLPQLDGRIVGGSATTISSFPWQ--ISLQRSGSH---SCGGSIYSANIIVTAAHCLQSV 76
            |.|| |:  |:..||:||..|.:..|||.  |..::.|:.   .|||::.:|..|:|||||:||:
Mosquito    91 TSPECGI--QVTDRIIGGQTTELEEFPWTALIEYRKPGNQYDFHCGGALINARYILTAAHCVQSL 153

  Fly    77 SA--SVLQVRAGSTYW-------------SSGGVVAKVSSFKNHEGYNA--NTMVNDIAVIRLSS 124
            ..  .:..||.|.  |             |:|.:..::.||..|.||:|  ....||||:|||..
Mosquito   154 PRGWQLNGVRLGE--WDLSTANDCSDGICSAGPIDLEIESFVAHAGYDAADTAHTNDIALIRLRQ 216

  Fly   125 SLSFSSSIKAISLATYNPAN-----GASAAVSGWGTQSSGSSSIPSQLQYVNVNIVSQSQCASST 184
            .::.|..|:.|.|....|..     |..:..:|||...|.|:|  .:...|.:.:...|:|....
Mosquito   217 DVASSEMIRPICLPLTEPQRSRNRVGTVSFAAGWGKTESASAS--ERKLKVELTVQDPSRCRQIY 279

  Fly   185 YGYGSQIRNTMICAAA-SGKDACQGDSGGPLV--SGGV--LVGVVSWGYG-CAYSNYPGVYADVA 243
            .|....::.:.:||.. .|||.|.|||||||:  |.|.  |:||||:|.. |..:.|||||.:|.
Mosquito   280 RGINIALKASQMCAGGLQGKDTCTGDSGGPLMAKSAGAWYLIGVVSFGLSKCGTAGYPGVYTNVV 344

  Fly   244 VLRSWVVS 251
            ....|:.|
Mosquito   345 EYLDWIES 352

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
alphaTry	NP_476771.1	Tryp_SPc	30..249	CDD:214473	85/251 (34%)
CLIPB2	XP_312956.3	CLIP	26..78	CDD:288855
		Tryp_SPc	102..350	CDD:214473	85/251 (34%)
		Tryp_SPc	103..353	CDD:238113	86/254 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910