DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment alphaTry and CLIPD6

DIOPT Version :9

Sequence 1:	NP_476771.1	Gene:	alphaTry / 48316	FlyBaseID:	FBgn0003863	Length:	256	Species:	Drosophila melanogaster
Sequence 2:	XP_312099.2	Gene:	CLIPD6 / 1273147	VectorBaseID:	AGAP002813	Length:	484	Species:	Anopheles gambiae

Alignment Length:	250	Identity:	81/250 - (32%)
Similarity:	122/250 - (48%)	Gaps:	35/250 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 RIVGGSATTISSFPWQISLQRSG-----SHSCGGSIYSANIIVTAAHCLQSVSASVLQVRAG--- 86
            |:|||....::.:||...:....     |..||||:.:...::|||||::...:|   ||.|
Mosquito   232 RVVGGVPAELNGWPWMALVGYKNTLGEVSFKCGGSLITKRHVLTAAHCIRRDLSS---VRLGEHD 293

  Fly    87 -STYWSSGGVVAKVSSFKNHEGYNANTMVNDIAVIRLSSSLSFSSSIKAISL---ATYNPAN--G 145
             ||...:..:...|..:::|..|:......|:||:.:...:.||.:||.|.|   .|....|  |
Mosquito   294 TSTDAETKHIDVPVVRYESHPSYDKKDGHTDLAVLYMEFEVQFSDAIKPICLPLSETIRSKNFIG 358

  Fly   146 ASAAVSGWG-TQSSGSSSIPSQLQYVNVNIVSQSQCASSTYGYG-----SQIRNTMICAAA--SG 202
            .:..|:||| ||..|.|:  :.||.:.:.|::..:|.:.....|     .|..|.::||..  .|
Mosquito   359 YTPFVAGWGRTQEGGKSA--NVLQELQIPIIANDECRTLYDKIGKVFSQKQFDNAVMCAGVIEGG 421

  Fly   203 KDACQGDSGGPLVSGG--------VLVGVVSWGYGCAYSNYPGVYADVAVLRSWV 249
            ||:|||||||||:...        ..||:||:|.|||.:..||||..||....|:
Mosquito   422 KDSCQGDSGGPLMLPQRFGTEFYYYQVGIVSYGIGCARAEVPGVYTRVASFVDWI 476

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
alphaTry	NP_476771.1	Tryp_SPc	30..249	CDD:214473	80/248 (32%)
CLIPD6	XP_312099.2	CLIP	25..80	CDD:288855
		CLIP	114..166	CDD:288855
		Tryp_SPc	232..476	CDD:214473	80/248 (32%)
		Tryp_SPc	233..479	CDD:238113	80/248 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910