DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment alphaTry and AgaP_AGAP013487

DIOPT Version :9

Sequence 1:	NP_476771.1	Gene:	alphaTry / 48316	FlyBaseID:	FBgn0003863	Length:	256	Species:	Drosophila melanogaster
Sequence 2:	XP_003436426.1	Gene:	AgaP_AGAP013487 / 11176153	VectorBaseID:	AGAP013487	Length:	308	Species:	Anopheles gambiae

Alignment Length:	256	Identity:	80/256 - (31%)
Similarity:	121/256 - (47%)	Gaps:	35/256 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 QLDGRIVGGSATTISSFPWQ--ISLQRS----GSHSCGGSIYSANIIVTAAHCLQSVSA--SVLQ 82
            ||..|::.|.:|.|..|||.  |..|:.    |.| ||||:.:...|||||||::|:..  .|.:
Mosquito    51 QLGDRVLSGQSTQIDEFPWTALIEFQKPDGSFGFH-CGGSLINDRYIVTAAHCIKSIPRDWKVQR 114

  Fly    83 VRAG-----------STYWSSGGVVAKVSSFKNHEGYNA--NTMVNDIAVIRLSSSLSFSSSIKA 134
            ||.|           :.:.|...:...:.....|.||:.  .:..||||:||.:..:::|.:::.
Mosquito   115 VRLGEWDLTSANDCQNEFCSDAPIDLDIEQIVVHTGYDTKDKSNANDIALIRFTRPVNYSQTVRP 179

  Fly   135 ISLATYNPANGAS--AAVS---GWGTQSSGSSSIPSQLQYVNVNIVSQSQCASSTYGYGSQIRNT 194
            |.|...:.....|  ..:|   ||...:|.::| ..:|: |.|.|.|..:||......|..::.|
Mosquito   180 ICLPLSSSLRNRSHDGLISYEVGWRKTNSATAS-EKKLK-VEVEIKSLQECAPIYERNGILLKQT 242

  Fly   195 MICA-AASGKDACQGDSGGPLV----SGGVLVGVVSWG-YGCAYSNYPGVYADVAVLRSWV 249
            .:|| ....||.|.|:|||||:    ....|:||.|:| ..|.....|.||.:||....|:
Mosquito   243 HMCAGGVRSKDTCSGNSGGPLMRQMTGSWYLIGVNSFGPRKCGTFGVPDVYTNVAEYVDWI 303

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
alphaTry	NP_476771.1	Tryp_SPc	30..249	CDD:214473	77/250 (31%)
AgaP_AGAP013487	XP_003436426.1	Tryp_SPc	55..303	CDD:214473	77/250 (31%)
AgaP_AGAP013487	XP_003436426.1	Tryp_SPc	59..306	CDD:238113	77/248 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910