Protein Alignment alphaTry and KLK11

DIOPT Version :9

• Sequence 1: NP_476771.1
• Gene: alphaTry / 48316
• FlyBaseID: FBgn0003863
• Length: 256
• Species: Drosophila melanogaster
• Sequence 2: XP_011524671.1
• Gene: KLK11 / 11012
• HGNCID: 6359
• Length: 307
• Species: Homo sapiens
• Alignment Length: 281
• Identity: 82/281 - (29%)
• Similarity: 132/281 - (46%)
• Gaps: 48/281 - (17%)

  Fly     5 VILLSAVVCALGGTVPEGLLPQLDGRIVGGSATTISSFPWQISLQRSGSHSCGGSIYSANIIVTA 69
            :|||:.....:||          :.||:.|......|.|||.:|.......||.::.:...::||
Human    38 LILLALATGLVGG----------ETRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTA 92

  Fly    70 AHCLQSVSASVLQVRAGSTYWSSGGVVAKVS-------------------------SFKNHEGYN 109
            ||||:...:............||...::.:|                         ||. |.|:|
Human    93 AHCLKPWVSLTSPTHVSPDLSSSNYCLSHLSRYIVHLGQHNLQKEEGCEQTRTATESFP-HPGFN 156

  Fly   110 ANTMV-----NDIAVIRLSSSLSFSSSIKAISLATYNPANGASAAVSGWGTQSSGSSSIPSQLQY 169
             |::.     |||.:::::|.:|.:.:::.::|::.....|.|..:||||:.||....:|..|:.
Human   157 -NSLPNKDHRNDIMLVKMASPVSITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRC 220

  Fly   170 VNVNIVSQSQCASSTYGYGSQIRNTMICAAA--SGKDACQGDSGGPLVSGGVLVGVVSWGYG-CA 231
            .|:.|:...:|.::   |...|.:||:||:.  .|||:||||||||||....|.|::|||.. ||
Human   221 ANITIIEHQKCENA---YPGNITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCA 282

  Fly   232 YSNYPGVYADVAVLRSWVVST 252
            .:..||||..|.....|:..|
Human   283 ITRKPGVYTKVCKYVDWIQET 303

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alphaTry	NP_476771.1	Tryp_SPc	30..249	CDD:214473	75/251 (30%)
KLK11	XP_011524671.1	Tryp_SPc	53..300	CDD:214473	75/251 (30%)
		Tryp_SPc	54..303	CDD:238113	75/253 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D469244at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X21
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.920