DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment alphaTry and F11

DIOPT Version :9

Sequence 1:	NP_476771.1	Gene:	alphaTry / 48316	FlyBaseID:	FBgn0003863	Length:	256	Species:	Drosophila melanogaster
Sequence 2:	NP_082342.1	Gene:	F11 / 109821	MGIID:	99481	Length:	624	Species:	Mus musculus

Alignment Length:	244	Identity:	86/244 - (35%)
Similarity:	123/244 - (50%)	Gaps:	17/244 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 QLDGRIVGGSATTISSFPWQISLQRSGSHSCGGSIYSANIIVTAAHCLQSV-SASVLQVRAGSTY 89
            :::.|:|||:|:....:|||::|..|..|.|||||.....|:|||||...: :...|:|..|...
Mouse   385 KINPRVVGGAASVHGEWPWQVTLHISQGHLCGGSIIGNQWILTAAHCFSGIETPKKLRVYGGIVN 449

  Fly    90 WS---SGGVVAKVSSFKNHEGYNANTMVNDIAVIRLSSSLSFSSSIKAISLATYNPANGASAA-- 149
            .|   .|....:|.....|:.|.......|||:::|.|:::::...:.|.|.:....|.....
Mouse   450 QSEINEGTAFFRVQEMIIHDQYTTAESGYDIALLKLESAMNYTDFQRPICLPSKGDRNAVHTECW 514

  Fly   150 VSGWG-TQSSGSSSIPSQLQYVNVNIVSQSQCASSTYGYGSQIRNTMICAA--ASGKDACQGDSG 211
            |:||| |...|  .:.|.||...|.:||..:|  .|.....:|.|.||||.  ..|||.|:||||
Mouse   515 VTGWGYTALRG--EVQSTLQKAKVPLVSNEEC--QTRYRRHKITNKMICAGYKEGGKDTCKGDSG 575

  Fly   212 GPLVS--GGV--LVGVVSWGYGCAYSNYPGVYADVAVLRSWVVSTANSI 256
            |||..  .||  |||:.|||.||.....||||.:||....|::....::
Mouse   576 GPLSCKYNGVWHLVGITSWGEGCGQKERPGVYTNVAKYVDWILEKTQTV 624

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
alphaTry	NP_476771.1	Tryp_SPc	30..249	CDD:214473	85/231 (37%)
F11	NP_082342.1	APPLE	20..103	CDD:128519
		APPLE	110..193	CDD:128519
		APPLE	200..283	CDD:128519
		APPLE	291..376	CDD:128519
		Tryp_SPc	389..617	CDD:214473	85/231 (37%)
		Tryp_SPc	390..617	CDD:238113	84/230 (37%)
		Heparin-binding. /evidence=ECO:0000250	547..550		0/2 (0%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910