DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment alphaTry and si:dkey-32n7.7

DIOPT Version :9

Sequence 1:	NP_476771.1	Gene:	alphaTry / 48316	FlyBaseID:	FBgn0003863	Length:	256	Species:	Drosophila melanogaster
Sequence 2:	XP_021335883.1	Gene:	si:dkey-32n7.7 / 108191692	ZFINID:	ZDB-GENE-121214-179	Length:	609	Species:	Danio rerio

Alignment Length:	258	Identity:	91/258 - (35%)
Similarity:	130/258 - (50%)	Gaps:	30/258 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 SAVVCALGGTVPEGLLP-QLDGRIVGGSATTISSFPWQISLQRSGSHSCGGSIYSANIIVTAAHC 72
            ||.||        |::| ......|||..::...:|||.||......:||||:.:...:::||||
Zfish   293 SAAVC--------GIIPVNSSNGTVGGQNSSAVHWPWQASLYWYSGQTCGGSLINKEWVLSAAHC 349

  Fly    73 LQSV-SASVLQVRAG---STYWSSGGVVAKVSSFKNHEGYNANTMVNDIAVIRLSSSLSFSSSIK 133
            .... :...|.|..|   ...:....:...|.:...|..||.||..||||::|||..::|:.||:
Zfish   350 FNGQRNGFYLTVILGPKTQNKYDPSRISRSVKAVIKHPYYNPNTNDNDIALVRLSFPITFTDSIR 414

  Fly   134 AISLA----TYNPANGASAAVSGWGTQSSGSSSIPSQ--LQYVNVNIVSQSQCASSTYGYGSQIR 192
            .:.||    .:|  :...:.::.|...|.| ..:||.  .|.|.|.::...|| :..||.|| |.
Zfish   415 PVCLAAEGSVFN--SDTESWITTWRNISDG-VPLPSPKIFQEVEVPVIGNRQC-NCLYGVGS-IT 474

  Fly   193 NTMICAA--ASGKDACQGDSGGPLVSG----GVLVGVVSWGYGCAYSNYPGVYADVAVLRSWV 249
            :.||||.  ..|||.||||||||:||.    .|..|:||:|.|||.|.:||||..|:..:.|:
Zfish   475 DNMICAGLLKEGKDLCQGDSGGPMVSNQSSVWVQSGIVSFGSGCAQSEFPGVYTRVSRYQEWI 537

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
alphaTry	NP_476771.1	Tryp_SPc	30..249	CDD:214473	84/234 (36%)
si:dkey-32n7.7	XP_021335883.1	NIDO	4..63	CDD:310601
		NIDO	141..272	CDD:322035
		Tryp_SPc	309..537	CDD:238113	84/232 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910