DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment alphaTry and tmprss2.15

DIOPT Version :9

Sequence 1:	NP_476771.1	Gene:	alphaTry / 48316	FlyBaseID:	FBgn0003863	Length:	256	Species:	Drosophila melanogaster
Sequence 2:	XP_031752206.1	Gene:	tmprss2.15 / 101732233	XenbaseID:	XB-GENE-22065943	Length:	504	Species:	Xenopus tropicalis

Alignment Length:	264	Identity:	99/264 - (37%)
Similarity:	148/264 - (56%)	Gaps:	27/264 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 AVVCALGGTVPE-----GLLPQLDGRIVGGSATTISSFPWQISLQR---SGSHSCGGSIYSANII 66
            :..||.|..|..     ||..::|.|||||:..::..:|||:.|.:   :..:.|||||.:.:.|
Frog   239 SATCASGNMVSLRCISCGLSTKVDSRIVGGTPASVGDWPWQVELLKLVGTSIYLCGGSIITPHWI 303

  Fly    67 VTAAHCL--QSVSASVLQVRAGS----TYWSSGGVVAKVSSFKNHEGYNANTMVNDIAVIRLSSS 125
            ||||||:  .:.:.|..:|.|||    :|:|:|..|.:...   |..|::.|.:.|:|:::|:::
Frog   304 VTAAHCVYGSTSTPSAFKVFAGSLTIQSYYSAGYTVERALV---HPSYSSYTQIYDVALLKLTAA 365

  Fly   126 LSFSSSIKAISLATYNP--ANGASAAVSGWGTQSSGSSSIPSQLQYVNVNIVSQSQCASSTYGYG 188
            |.|:::::.:.|.....  |.|....:|||||.:.| .||...|...:|.|:|.:.|..:.. ||
Frog   366 LVFTTNLRPVCLPNVGMPWAEGQPCWISGWGTTAEG-GSISKNLMAASVPIISSTTCNQAAV-YG 428

  Fly   189 SQIRNTMICAA--ASGKDACQGDSGGPLV----SGGVLVGVVSWGYGCAYSNYPGVYADVAVLRS 247
            ..|.:||:||.  :.|.|.||||||||||    |...|||..|||||||.:..||||.:|.|...
Frog   429 GAISSTMMCAGYLSGGTDTCQGDSGGPLVTKTNSLWWLVGDTSWGYGCARAYKPGVYGNVTVFIE 493

  Fly   248 WVVS 251
            |:.|
Frog   494 WIYS 497

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
alphaTry	NP_476771.1	Tryp_SPc	30..249	CDD:214473	90/235 (38%)
tmprss2.15	XP_031752206.1	LDLa	93..121	CDD:238060
		SRCR_2	164..259	CDD:406055	6/19 (32%)
		Tryp_SPc	265..498	CDD:238113	91/238 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X21
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910