DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment alphaTry and tmprss15

DIOPT Version :9

Sequence 1:	NP_476771.1	Gene:	alphaTry / 48316	FlyBaseID:	FBgn0003863	Length:	256	Species:	Drosophila melanogaster
Sequence 2:	XP_031752048.1	Gene:	tmprss15 / 100490249	XenbaseID:	XB-GENE-999987	Length:	994	Species:	Xenopus tropicalis

Alignment Length:	245	Identity:	77/245 - (31%)
Similarity:	128/245 - (52%)	Gaps:	20/245 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 LLPQLDG-RIVGGSATTISSFPWQISLQRSGSHSCGGSIYSANIIVTAAHCL--QSVSASVLQVR 84
            |:|...| :|||||...:.::||.:||..:...:||.|:.:...:|:||||:  :::..|..:.|
Frog   751 LVPIKSGSKIVGGSDAALGAWPWIVSLYYNDRQTCGASLVNQEWLVSAAHCVYGRNLIPSNWKAR 815

  Fly    85 AG---STYWSSGGVVAK-VSSFKNHEGYNANTMVNDIAVIRLSSSLSFSSSIKAISLATYNP--A 143
            .|   :...:...:..: :.....:..||..|..:||.::.|...:::|..|:.|.|...:.  :
Frog   816 LGLHTNLNLTQPQIATQMIDQIVINPQYNRRTKDSDIVMMHLQFKVNYSDYIQPICLPETDQEFS 880

  Fly   144 NGASAAVSGWG-TQSSGSSSIPSQLQYVNVNIVSQSQCASSTYGYGSQIRNTMICAA--ASGKDA 205
            .|.:.:::||| |||.|  .:|:.||...:.::|..:|......|  .|.:.|:|..  ..|.|.
Frog   881 VGINCSIAGWGRTQSGG--PVPNILQEAEIPLISNHKCQQQMPEY--NITDNMVCGGYEEGGIDT 941

  Fly   206 CQGDSGGPLV----SGGVLVGVVSWGYGCAYSNYPGVYADVAVLRSWVVS 251
            ||||||||::    :...||||.|:|||||..:.||||..|....:|:.|
Frog   942 CQGDSGGPMMCQQNNEWFLVGVTSFGYGCAQPSRPGVYVRVTEFTNWIKS 991

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
alphaTry	NP_476771.1	Tryp_SPc	30..249	CDD:214473	72/233 (31%)
tmprss15	XP_031752048.1	SEA	36..>103	CDD:396113
		LDLa	157..190	CDD:197566
		CUB	199..305	CDD:238001
		MAM	321..478	CDD:395504
		CUB	501..608	CDD:395345
		LDLa	620..654	CDD:238060
		SR	655..746	CDD:214555
		Tryp_SPc	760..991	CDD:238113	73/234 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910